Conditional gene regulation in Drosophila through binary expression systems like the LexA-LexAop system provides a superb tool for investigating gene and tissue function. To increase the availability of defined LexA enhancer trap insertions, we present molecular, genetic and tissue expression studies of 301 novel Stan-X LexA enhancer traps derived from mobilization of the index SX4 line. This includes insertions into distinct loci on the X, II and III chromosomes that were not previously associated with enhancer traps or targeted LexA constructs, an insertion into ptc, and seventeen insertions into natural transposons. A subset of enhancer traps was expressed in CNS neurons known to produce and secrete insulin, an essential regulator of growth, development and metabolism. Fly lines described here were generated and characterized through studies by students and teachers in an international network of genetics classes at public, independent high schools, and universities serving a diversity of students, including those underrepresented in science. Thus, a unique partnership between secondary schools and university-based programs has produced and characterized novel resources in Drosophila, establishing instructional paradigms devoted to unscripted experimental science.
A partir del análisis de la Sociedad Musical de Socorros Mutuos de Valparaíso (SMSMV), este artículo propone incorporar la perspectiva del trabajo a los estudios musicales, entendiendo de esta forma a los músicos como trabajadores que en ciertos momentos de la historia se han organizado para mejorar sus condiciones de vida y laborales. Esto implica comprender la música en su múltiple dimensión musical, histórica, económica y social.
Que imagem de escritor se pode deduzir dessa estranha compulsão à ubiquidade? A de um autor de culto? Um autor para consumidores selvagens de histórias? Um autor para vanguardistas? Um autor para aprendizes de escritores? (PAULS, 2012, p. 169
Conditional gene regulation in Drosophila through binary expression systems like the LexA-LexAop system provides a superb tool for investigating gene and tissue function. To increase the availability of defined LexA enhancer trap insertions, we present molecular, genetic and tissue expression studies of 301 novel Stan-X LexA enhancer traps derived from a screen with the index SX4 line. This includes insertions into distinct loci on the X, II and III chromosomes that were not previously associated with enhancer traps or targeted LexA constructs. A subset of enhancer traps was expressed in CNS neurons known to produce and secrete insulin, an essential regulator of growth, development and metabolism. Fly lines described here were generated and characterized through studies by students and teachers in an international network of genetics classes at public and independent high schools and universities serving a diversity of students, including those underrepresented in science. Thus, a unique partnership between secondary schools and university-based programs has produced and characterized novel resources in Drosophila, establishing instructional paradigms devoted to unscripted experimental science.
resumen En este trabajo abordo las relaciones entre firma y autoría en Budapeste, de Chico Buarque y en Dívorcio, de Ricardo Lísias. Me interesa detenerme en el gesto como borde inexpresivo que se vuelve presente en el uso de las firmas autorales que las dos ficciones realizan. Una como juego de espejos entre un ghostwriter que se vuelve reconocido en un país extranjero y Chico Buarque, cuyo impacto como escritor crece a partir de la publicación del libro. Además, me detengo en cómo la versión cinematográfica de Walter Carvalho de 2009, Budapeste, repone el mismo juego ficcional de la novela, ahora arrastrado al cine y abriendo una zona de autoría colectiva respecto de la ficción. La segunda novela, Dívorcio, de Ricardo Lísias, permite detenernos en un juego coincidente entre firma autoral, narrador y personaje, pero a partir de una devaluación de la imagen autoral que esa firma escribe. Estas dos formas me permiten repensar qué significa ser un autor y leer algunas de las condiciones de la ficción brasileña - y conosureña - del presente.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.