Direct costs for robot-assisted surgery were significantly lower than equivalent open surgery. Factors reducing robot-assisted surgery costs included: A consistent and trained robotic surgery team, an extensive history of performing urologic robotic surgery, selection of patients for robotic surgery who otherwise would have had longer hospital stays after open surgery, and selection of procedures without a laparoscopic alternative. The high indirect costs of robot purchase and maintenance remain major factors, but could be overcome by high surgical volume and reduced prices as competitors enter the market.
Near infrared imaging offers a feasible way to obtain live, dynamic images of urine flow and ureteral peristalsis. Qualitative and quantitative parameters were comparable to those of conventional imaging. Findings support fluorescence imaging as an accurate, easy to use method of diagnosing ureteropelvic junction obstruction.
Background/Purpose: Telehealth has evolved over the past several decades to address varying medical needs. Most recently, it has been widely utilized as a result of the COVID-19 pandemic. Most previous studies have not performed in-depth analyses of patient satisfaction with telehealth technologies. This project investigated patient satisfaction with the abrupt implementation of telemedicine within pediatric surgical subspecialties during the COVID-19 pandemic. Materials and Methods: We conducted a single-center review to determine patients' satisfaction with telemedicine during the early stages of the pandemic. Surveys were distributed to patients who completed a telemedicine video visit within a pediatric surgical subspecialty at Connecticut Children's Medical Center between March 16 and May 16, 2020. Results: A total of 1,608 patients were contacted, with 457 surveys completed (28.4%). Of all respondents, 95.6% were ''very satisfied'' or ''satisfied'' with their overall telemedicine appointment. Seventy-three percent reported no difficulty with completing their visit. Eighty-seven percent would consider another telemedicine visit again in the future. No significant difference was found between the payor mix for telemedicine and in-person appointments. Conclusions: The implementation of telemedicine at Connecticut Children's Medical Center during the COVID-19 pandemic was successful despite numerous barriers to use. Families not only showed high rates of satisfaction with the overall visit and provider interaction, but also an overwhelming openness to future use of telehealth.
Study Type – Aetiology (case series)
Level of Evidence 4
What's known on the subject? and What does the study add?
Genetic linkage to distinguish loci for VUR has been previously described in several autosomal chromosomes. Although there are numerous explanations for the dissimilar findings, e.g. multifactorial etiology of VUR and hereditary miscellany among studied populations, clinical diversity between males and females may indicate a central gender‐specific genetic susceptibility.
Early studies suggested the presence of modified VUR gene(s) on the X‐chromosome, accounting for the higher incidence of this disorder among female members in the pedigrees studied. On the other hand male‐to‐male transmission and a higher ratio of females to males argued against X‐linked inheritance. More recently, additional chromosomal regions (i.e. chromosomes 1–7, 10–13, and 18–22) have been identified for VUR by using single nucleotide polymorphism‐genome‐wide linkage analysis.
This is the first study to show that there is autosomal difference in VUR expression in males and females. This genotype variability may be the basis for the clinical differences between genders in children with VUR.
OBJECTIVE
To assess gender‐specific genetic differences in the susceptibility loci for vesico‐ureteric reflux (VUR) in families who have two or more affected children.
PATIENTS AND METHODS
A genome‐wide linkage analysis of VUR with high‐density single nucleotide polymorphisms was conducted in 98 families with two or more affected children.
A total of 221 affected offspring (123 sibling pairs) were included in the analysis.
Genomic DNA was extracted from blood or saliva from all the patients.
Data was stratified and analysed according to clinical presentation and gender of the proband and affected siblings.
RESULTS
Using the affected sib‐pair method, statistically significant peaks were found on chromosomes 1 (logarithm of odds, base10 [LOD] 4.4) and 5 (LOD 3.7) in males and on chromosomes 3 (LOD 3.5), 13 (LOD 4.5), and 15 (LOD 3.4) in females.
CONCLUSION
This genotype variability might be the basis for the clinical differences between genders in children with VUR. Our data might be the first step to understanding the genetic background behind the gender‐specific differences of VUR and more clearly defining the genetically different subgroups of VUR.
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