The case records and owners of seventy–two dogs with perineal hernia seen at the University of Pennsylvania Veterinary Hospital were surveyed. The condition was seen in older male dogs, most of which presented with perineal swelling and straining to defaecate. Most dogs were treated by perineal herniorrhaphy. The incidence of recurrence in those dogs treated surgically was 46%. Recurrence was more common when the surgery had been performed by inexperienced surgeons, in those dogs which had been treated surgically elsewhere, and in those dogs in which the time period from surgery to survey was more than 1 year. Other complications occurring were wound infection, faecalincontinence, urinary problems and lameness. Most owners of dogs which were alive at the time of the survey were satisfied with the results of treatment. Castration had no effect on the incidence of recurrence or development of a hernia on the opposite side to that repaired initially. Résumé. On a étudié les dossiers de soixante‐douze chiens avec des nernies perinéales, vus à l'Hǒpital vétérinaire de l'Université de Pennsylvanie. On a observé la condition chez des chiens mǎles plus ǎgés dont la plupart souffraient d'enflure périnéale et devaient faire tous leurs efforts pour aller à la selle. La plupart des chiens ont été traités par suture de hernie périnéale. Le taux de récidive chez ces chiens traités par chirurgie, a été de 46%. Les récidives ont été plus communes quand la chirurgie a été pratiquée par des chirurgiens peu expérimentés, chez ces chiens traités par chirurgie ailleurs, et chez ceux pour lesauels le laps de temps d'une opération à une autre était de plus d'un an. Une infection de la plaie, une incontinence de fèces, des problèmes urinaires et un état de claudication se comptent parmi les complications survenues. La plupart des propriétaires dont les chiens étaient vivants au moment de cette étude ont été satisfaits des résultats. La castration n'a pas eu d'effet sur la récidive ou le développement d'une hernie du cǒté opposé de celle qui avait été réparée auparavant. Zusammenfassung. Eine Aufzeichnung von Fàllen mit perinealer Hernie in 72 Hunden, die man im Tierǎrztlichen Krankenhaus der Universitǎt von Pennsylvanien sah, wurde iiberblickt. Man fand den Zustand in àlteren mànnlichen Hunden, von denen die meisten périnéale Sch‐wellung und Anstrengung beim Dafàzieren zeigten. Die neisten Hunde wurden durch périnéale Bruchnaht behandelt. Der Vorfall von erneutem Auftreten dieser Beschwerden in jenen Hunden die chirurgisch behandelt wurden, war 46%. Emeutes Auftreten war hàufiger, wenn die Opération von unerfahrenen Ghirurgen ausgefùhrt wurde, in den Hunden die anderswo chirurgisch behandelt waren und in Jenen Hunden, deren Zeitspanne von einer Opération zur anderen mehr als ein Jahr betrug. Andere Komplikationen die vorkamen ware Wundinfektion, Nichthalten‐kǒnnen des Kotes, urinàre Problème und Lahmheit. Die meisten Besitzer der Hunde die zur Zeit d...

Aims-To determine the role ofinterstitial myofibroblasts in the progression of membranous nephropathy; and to assess the predictive value of quantifying myofibroblasts in determiniing long term renal outcome.

This study examines effects of variations in fiber content on nutrient assimilation, fecal output, and gastrointestinal transit time in the dog. Four normal Beagles were fed four diets in a randomized block design. The basal diet was a canned, balanced, meat-based dog food (Alpo Trio) to which added 3, 6, and 9% by weight of alpha cellulose (Solka Flok). Food intake and fecal outputs were recorded for 5-day periods. Samples of diets and fecal collections were analyzed for dry matter, nitrogen, fat, carbohydrate and ash; digestibilities were calculated. Transit times were measured by a radiographic marker technique. Fecal weight and water increased linearly; digestibility of dry matter decreased from 90 to 70% and ash from 43 to 32% with added fiber. Responses of protein, carbohydrate and fat were less pronounced but were regular; regressions of their digestibilities on added fiber were significant. Regression estimate of true digestibility for alpha-cellulose was 6%. Intestinal transit time decreased from a mean of 37.4 to 28.7 hours with added fiber. Decreased intestinal time would contribute to depression of fry matter digestibility. Increased fecal water output probably also reflected retention by fiber.

Texturized vegetable protein from soy (TVP) is widely used in canned dog foods, but its nutritional value remains in doubt. This study compared apparent prececal and total intestinal digestibility when four canned diets containing reciprocal proportions of protein from TVP (0 to 57%) and from beef (100 to 43%) were fed to eight cannulated dogs. As dietary TVP increased, the following linear changes were observed (P < 0.05): prececal and total intestinal protein digestibility decreased slightly from 77 to 71% and 86 to 80%, respectively; prececal amino acid digestibility decreased in parallel with protein; prececal carbohydrate digestibility decreased markedly from 80% to 62% and carbohydrate disappearance in the large intestine increased from 8 to 22%; prececal sodium digestibility decreased markedly (from 37 to 4%); and prececal potassium digestibility decreased (from 93 to 85%). Total intestinal digestibility of sodium and potassium decreased little (from 97 to 95% and from 98 to 97%, respectively); fecal mass and water content increased markedly (from 98 to 174 g/d and from 61 to 72%, respectively); and fat digestibility was unaffected. Prececal phosphorus digestibility from two diets containing TVP was lower than that from the all-beef diet (13 and 17%, vs 26%, P < 0.05). In conclusion, TVP is a useful source of protein in canine canned diets because amino acids from TVP are almost as digestible as those from beef in the canine intestine. Nevertheless, soy carbohydrate is poorly digested and large amounts of TVP inhibit small intestinal electrolyte digestibility and increase fecal water content.

Colonic mucosal samples were obtained every 4 weeks for 13 months from 6 clinically normal dogs and from 47 dogs with a clinical diagnosis of chronic inflammatory bowel disease. All samples were graded on a scale of 0-5, based upon the quantity of lymphocytes and plasma cells in the lamina propria, epithelial changes, and the presence of ulcers and erosions. A grade of less than or equal to 2.0 was considered normal and was assigned to 77 of 78 samples from clinically normal dogs and 28 of 48 samples from dogs with diarrhea. A transient increase in cellularity was noted in 1 sample from 1 control dog. Nineteen dogs with clinical disease had obvious histologic abnormalities. The grading scheme described provides the pathologist with an objective criterion for the microscopic evaluation of colonic mucosal samples obtained by endoscopic techniques and offers clinicians a method of assessing the dog's progress and response to therapy.

No abstract

This article describes the occurrence of Filaroides osleri infestation in a 11/2 year‐old male Miniature Schnauzer dog in which the presenting sign was recurrent pneumothorax, Diagnosis was made by direct visualization of the lesions caused by the parasite at bronchoscopic examination. Successful treatment consisted of endobronchial removal of the obstructing nodules. The unusual presenting signs exhibited by the dog are discussed in the light of current knowledge of the disease. Résumé. Cet article décrit l'apparition d'infestation ‘Filaroides’ osleri dans un chien Schnauzer‐nain mâle âgé d'un an et demi dans lequel le signe apparent se traduisait par un pneumothorax périodique. On a fait le diagnostique par une observation visuelle directe des lésions causées par le parasite à l'examen bronchoscopique. Le traitement qui a réussi a consisté en l'enlèvement endobronchique des nodules obstructifs. Les signes rares montrés par le chien sont discutés à la lumière de la connaissance actuelle de la maladie. Zusammenfassung. Dieser Artikel beschreibt das Vorkommen des Befalls ‘Filaroides osleri’ in einem Kleinschnauzer Hund, der eineinhalb Jahre alt ist, in dem das sichbare Zeichen, wiederkehrender Pheumathode war. Die Diagnose wirt von director Sichtbarmachung der Verletzungen gemacht, die vom Parasit in bronchoscopisher Untersuchung verursachten. Die glückliche Behandlung bestand aus inner bronchialer Abtrennung der verstopfenden Knötchen. Die aussergewöhnliche Zeichen vorzeigten vom Hund, werden im Lichte vom laufenden Wissen der Krankheit besprochen.

Summary Developmental changes of the gastrointestinal tract were probably responsible for the changes in faecal composition during the first week of the foals' life, which resembled small intestinal ingesta of adult horses, suggesting a minimal colonic modification. Faecal composition at the time of foal heat diarrhoea was suggestive of a secretory‐type diarrhoea, in that the electrolyte concentration accounted for most of faecal osmolality and the faecal pH was alkaline. After foal heat diarrhoea faecal composition slowly approached that of adult horses. These data suggest that foal heat diarrhoea is most likely caused by hypersecretion in the small intestinal mucosa, which may overwhelm an immature colon that is unable to compensate by increased fluid and electrolyte absorption.