IACT-AC reduced respiratory artifacts and improved PET/CT matching similarly to ACT-AC. It is a promising low-dose alternate of ACT for cardiac PET/CT.
Previously we demonstrated the ef interpolated average CT (IACT) for attenuatio in PET in simulations and clinical patients. T evaluate the performance of IACT for thor different sizes, uptake ratios and locations. The was used to simulate noisy 18 F-FDG distribut clinical count level with respiratory motion am and 3 cm. The average activity and a represented static PET and cine average (CA IACT was generated by the end-inspiration an phases of the attenuation maps (HCT-in and deformable registration method. Spherical 10 lesions were simulated at 4 locations individua lower left lung (LLL), lower right lung (LRL), (MRL) and upper right lung (URL). Four targ ratios (TBR), including 4:1 and 8:1 for respira cm, 6:1 and 12:1 for respiratory motion of 3 cThe noisy sinograms with attenuation modelin and reconstructed with different AC maps by for Tomographic Image Reconstruction), using to 300 updates. Normalized mean square error information (MI) and TBR were analyzed. Th results showed that PET CACT and PET IACT wer the original phantom as compared to PET HCT differences between CACT/IACT and HCTs significant for lesions in the lower lung with P higher TBR and PET HCT-in showed lower TBR PET CACT /PET IACT for all lesion sizes, up respiratory motion amplitudes. The TBRs for 1 more difficult to be recovered in all AC schem localization and more stable quantitation for characteristics make IACT a good alternate for to conventional HCT/CACT.
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