The Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome (NBCCS), is an infrequent multisystemic disease inherited in a dominant autosomal way, which shows a high level of penetrance and variable expressiveness. It is characterized by keratocystic odontogenic tumors (KCOT) in the jaw, multiple basal cell nevi carcinomas and skeletal abnormities. This syndrome may be diagnosed early by a dentist by routine radiographic exams in the first decade of life, since the KCOTs are usually one of the first manifestations of the syndrome. This article paper reports the case of a patient, a 10-year-old boy with NBCCS, emphasizing its clinical and radiographic manifestations. This study highlights the importance of health professionals in the early diagnosis of NBCCS and in a preventive multidisciplinary approach to provide a better prognosis for the patient.

ResumoIntrodução: Os antimicrobianos são caracterizados como um dos mais notáveis exemplos do avanço da Medicina moderna. Contudo, a adaptabilidade dos microrganismos propicia resistência a determinados antimicrobianos. Objetivo: Apresentar, por meio de pesquisa realizada com alunos do curso de Odontologia e Cirurgiões-Dentistas na cidade de Aracaju-SE, um perfil do conhecimento destes sobre antibioticoterapia, propondo oferecer uma oportunidade de identificar e reconhecer os riscos relacionados à administração incorreta destes fármacos. Material e método: Investigação observacional, transversal, com base em um questionário respondido por 80 alunos do curso de Odontologia e 50 Cirurgiões-Dentistas, escolhidos de forma aleatória, para verificar o conhecimento sobre o tema proposto. Resultado: Dentre os entrevistados, aproximadamente 40% eram profissionais e 60% acadêmicos de Odontologia; destes, cerca de 40% relataram que prescrevem utilizando como critério de seleção que o antimicrobiano seja seletivo e bactericida, enquanto que 90% dos entrevistados afirmam prescrever antibiótico somente quando necessário, como forma de evitar a resistência bacteriana. Conclusão: De acordo com a metodologia empregada, pode-se concluir que os dois grupos mostraram desconhecimento sobre a diferença entre antibioticoterapia, profilaxia antimicrobiana e terapêutica medicamentosa.Descritores: Antimicrobianos; prescrição inadequada; Odontologia. AbstractIntroduction: Antimicrobial agents are a striking example of the evolution of modern medicine. However the adaptability of microorganisms provides resistance to certain antimicrobial drugs. Objective: To assess the knowledge of dentistry undergraduate students and dentists in the city of Aracaju, Sergipe State, about antibiotic therapy, thus providing an opportunity to identify and recognize the risks related to improper administration of these drugs. Material and method: This is an observational, cross sectional study based on a questionnaire given to 80 undergraduate students of dentistry and 50 dentists, ramdomly chosen, to assess the knowledge on the matter. Result: Among the interviewees, about 40% were dentists and 60% were dentistry students, 40% of respondents reported to prescribe antimicrobials using as selection criteria that it be selective and bactericidal, and 90% of respondents said they prescribe antibiotics only when necessary, in order to avoid bacterial resistance. Conclusion: According to the methodology applied it can be concluded that both groups showed lack of knowledge about the difference between antibiotic therapy, antimicrobial prophylaxis and drug therapy.

INTRODUCTION: The incidence of oral cancer varies widely in the world, with two thirds of cases diagnosed in developing countries. OBJECTIVE: To investigate the epidemiology of deaths from oral cancer and the spatial distribution in the city of Aracaju in the state of Sergipe between 2000 and 2009. MATERIAL AND METHOD: Data were collected using the Mortality Information System (MIS) of Aracaju/SE at the DATASUS website and were tabulated using the software TABWIN 3.4. The geographic distribution of deaths by neighborhoods of that city was visualized. RESULT: Of the 78 deaths, 61 (78.2%) were male. The mean age was 64.23 years. Individuals of mixed ethnicity had a higher death frequency (34.6%). Regarding education, the majority of death certificates recorded the option ignored, followed by individuals with 1 to 3 years of study. The anatomical sites most affected were unspecified parts of the mouth (43.6%). The spatial distribution analysis indicated that neighborhoods such as Santos Dumont, Luzia, Atalaia, Santa Maria, Cidade Nova and Industrial had the highest death frequencies. CONCLUSION: Males between the fifth and sixth decades of life of mixed ethnicity, low education and in neighborhoods with low and very low standards of living constitute the epidemiological profile for deaths from oral cancer.

The role of human papillomavirus (HPV) in oral carcinogenesis is still controversial as detection rates of the virus in oral cavity reported in the literature varies greatly. Objective The aim of this study was to evaluate the frequency of HPV infection and its genotypes in patients with oral lesions at the Ambulatory of Oral Diagnosis of the Federal University of Sergipe, Brazil.Material and Methods We conducted a molecular study with 21 patients (15 females) aged from two to 83 years with clinically detectable oral lesions. Samples were collected through exfoliation of lesions and HPV-DNA was identified using MY09/11 and GP5+/6+ primers. Genotyping was performed by multiplex PCR.Results Benign, premalignant and malignant lesions were diagnosed by histopathology. HPV was detected in 17 samples. Of these, HPV-6 was detected in 10 samples, HPV-18 in four and HPV-16 in one sample. When samples were categorized by lesion types, HPV was detected in two papilloma cases (2/3), five carcinomas (5/6), one hyperplasia (1/1) and nine dysplasia cases (9/11).Conclusion Unlike other studies in the literature, we reported high occurrence of HPV in oral lesions. Further studies are required to enhance the comprehension of natural history of oral lesions.

Plasma cell cheilitis (PCC) is an inflammatory disorder of unknown etiology that affects the lip. It is characterized histologically by a dense infiltrate of plasma cells with a variety of clinical features. The response to different therapeutic modalities is controversial, especially regarding the effectiveness of corticosteroids. We present a case of a 56-year-old Caucasian man with a painful ulcerated and crusted area in the lower lip, resembling a squamous cell carcinoma or actinic cheilitis. Topical corticosteroid was used for one week, which resulted in partial regression and motivated a biopsy. The histological examination provided the diagnosis of PCC. The patient has been disease-free for six months. We also provide a discussion on the criteria of differential diagnosis and management of this rare condition.

ResumoObjetivo: Analisar a resistência à fratura por fadiga dos conjuntos implante-pilar, nos tipos reto e angulado, submetidos a cargas cíclicas similares às mastigatórias. Material e método: Foram utilizados 32 implantes (3,75 × 11 mm) com sistema cone Morse e 32 pilares, separados em dois grupos: pilares retos e angulados (n=16) (Neodent, Curitiba, PR, Brasil). Os conjuntos foram submetidos a testes cíclicos em equipamento servo-hidráulico, fixando-se o número de ciclos em cinco milhões. Conclusão: Os dois tipos de pilares (retos e angulados), em condições in vitro, comportaram-se estatisticamente de forma semelhante, sendo aceita a hipótese nula de que não há diferença de resistência à fratura entre os grupos.Descritores: Implantes dentários; resistência de materiais; fenômenos mecânicos. AbstractObjective: The aim of this study was to verify the fatigue fracture resistance of the implant-abutment joint, in straight and angled types, subject to cyclic loads similar to chewing. Material and method: It was used 32 implants system (3.75 × 11mm) with Morse taper and 32 abutment, divided in two groups: abutment straight and angled (n = 16) (Neodent, Curitiba, PR, Brazil). The sets were submitted to cyclic testing using servo-hydraulic equipment, fixing the number of cycles at 5 million. It was evaluated the number of cycles, load and moment force of the samples. The Fisher test and ANOVA were applied (p<0,005). Fractured samples were analyzed in the scanning electron microscopy (SEM). Result: Straight abutment, four resisted the cycles number established, supporting loads between 470N and 510N. Angled abutment: nine resisted to loads between 570N and 890N. Regarding the fractured samples below the number of cycles, in the straight abutment, nine fractured with loads between 470N and 630N. In the angled abutment, five fractured with loads ranging from 760N and 890N. The moment of the force was calculated for each joint implant-abutment (Averages: Straight Group -4335,23Nmm, angled Group -3923,37Nmm). Conclusion: Two types of abutments (straight and angled), in vitro conditions, statistically behaved similarly, and accepts the null hypothesis that there is no difference in fracture resistance between groups.Descriptors: Dental implants; material resistance; mechanical phenomena. INTRODUÇÃOO uso de implantes dentários osseointegrados tornou-se modalidade previsível de reabilitação bucal, confi rmada pelo alto sucesso em restaurações unitárias, parciais ou completas dos arcos edêntulos 1,2 . Entretanto, apesar do sucesso dos implantes osseointegrados, problemas de ordem mecânica, como a soltura ou fratura do pilar, o afrouxamento do parafuso de fi xação de coroas unitárias e a instabilidade protética, são problemas comumente relatados na literatura 3 .Durante os movimentos mastigatórios, os dentes naturais e os componentes protéticos são submetidos a cargas geradas pelo contato entre elementos antagonistas, de forma direta ou através da interposição de alimentos 4,5 . São geradas tensões na coroa a partir

Introduction: The adaptation of prostheses fixed over implants involves biomechanical aspects that are directly associated with treatment success. Objective: The aim of this in vitro study was to evaluate the presence of microgaps in the abutment/inner connection interface of cone morse dental implants. Materials and methods: Two groups of implants were analyzed. The first group (n = 16) employed single-manufacturer dental implants and abutments, whereas the second group (n = 16) combined multi-manufacturer materials. The sets were analyzed through scanning electron mi­croscopy, wherein microgaps between the implant connection and the abutment were observed. Results: Group 1 had an average microgap of 5.69 μm (SD ± 8.46 μm). Group 2 had an average microgap of 1.24 μm (SD ± 0.44 μm). A significant difference was found between the two groups (p = 0.002). Conclusion: Within the limitations of this study, results suggest that the group formed by multi-manufacturer implants and abutments (group 2) had smaller microgap values, and, therefore, a higher in vitro adaptation of components. DESCRIPTORS | Dental Implants; Dental Abutments; Scanning Electron Microscopy.

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