Despite the high level achieved in the field of shoulder surgery, a global consensus on rotator cuff tears management is lacking. This work is divided into two main sessions: in the first, we set questions about hot topics involved in the rotator cuff tears, from the etiopathogenesis to the surgical treatment. In the second, we answered these questions by mentioning Evidence Based Medicine. The aim of the present work is to provide easily accessible guidelines: they could be considered as recommendations for a good clinical practice developed through a process of sys- © C I C E d i z i o n i I n t e r n a z i o n a l i tematic review of the literature and expert opinion, in order to improve the quality of care and rationalize the use of resources. KEY WORDS: rotator cuff tears, Guidelines. IntroductionThe pathologies of the rotator cuff are common and they can be considered as a natural decline of the muscletendon unit in aging with statistically significant increase in frequency after 50 years. The painful shoulder is related in 30-70% of cases to disorders of the rotator cuff. The incidence of rotator cuff tears varies between 5 and 40%, although it is very difficult to establish the real incidence of these lesions, which are often asymptomatic. Currently, the pathology of the rotator cuff is considered to be multifactorial, because extrinsic and intrinsic factors play important roles, although it remains unclear the specific weight of each of these factors (Tab. 1). and often increased in number. staining eosinophilic There is a loss of orientation of homogeneous preparation the cores in relation to the bundles with hematoxylin/eosin. of collagen fibers. Chromatin has a dark color. Muscles, Ligaments and Tendons Grade 4 SevereComplete loss of orientation of The cores are reduced in number, Hyalinization with a homogeneous degeneration the collagen fiber bundles.small, dark and round. appearance. I.S.Mu.L.T -Rotator Cuff Tears Guidelines Grade 1The nuclei become more Colorable mucin between Decreased polarization Occasional clusters oval or round in shape fiber bundles but still fibers: separation of the of capillaries, less than without large cytoplasm. discrete number. individual fibers with one per 10 fields at high maintenance of the magnification. demarcation of the beams. Grade 2The nuclei are circular, Colorable mucin between Separation of the fibers 1-2 cluster of capillaries slightly widened and the fibers with loss with loss of demarcation for 10 fields at high a small amount of demarcation and a clear loss of normal magnification. of cytoplasm becomes of the beams. polarization. visible. Grade 3The nuclei are round, Abundant mucin among Demarcated separation More than two clusters wide with abundant poor colorable collagen. of fibers with complete to 10 fields at high cytoplasm and loss of architecture. magnification. the formation of a gap (chondroid change). © C I C E d i z i o n i I n t e r n a z i o n a l i MethodologyThe Authors were divided into four groups: -Coordinator: he conce...

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Fragility fracture healing is impaired in diabetic patients. Radiographic and molecular patterns confirmed that the most compromised fracture-healing phase is at 4 weeks after surgery, during callus mineralization.

Despite the high level achieved in the field of shoulder surgery, a global consensus on rotator cuff tears management is lacking. This work is divided into two main sessions: in the first, we set questions about hot topics involved in the rotator cuff tears, from the etiopathogenesis to the surgical treatment. In the second, we answered these questions by mentioning Evidence Based Medicine. The aim of the present work is to provide easily accessible guidelines: they could be considered as recommendations for a good clinical practice developed through a process of systematic review of the literature and expert opinion, in Guidelines order to improve the quality of care and rationalize the use of resources.

Backgrounds Chronic osteomyelitis is a major challenge in orthopaedic surgery; it is the result of open fracture, periprosthetic infection and septic arthritis. Osteomyelitis leads to fracture nonunion. The treatment of bone infection and infected nonunion consists primarily of the complete removal of infected and avascular bone and soft tissue from the surgical site, followed by local and systemic pathogen-specific antibiotic therapy and temporary stabilisation, but may lead to massive skeletal and soft tissue defects. The use of free or pedicled vascularised bone transfers and callus distraction techniques (bone transport) has been recommended for large bone defects. The aim of this study is to evaluate the results of patients affected by infected non-unions of the lower limbs, treated with a corticoperiosteal flap from the medial femoral condyle and to investigate the donor site morbidity of this flap. Materials and methods The patients were 11 males (average age of 45.6 years), who presented a nonunion of the tibial diaphysis in 7 cases and non-union of femoral diaphysis in 4 cases, treated with free or pedicled corticoperiosteal flap. In all patients, surgical debridement was performed before the flap of infected bone and soft tissues that would not contribute to wound healing. Clinical and radiographic evaluations of the recipient site were performed. Preoperative and postoperative X-ray and MRI scans after the 3-year follow-up of the donor site were performed, in order to observe possible bone restoration and any complications. Results The patients reported complete clinical and radiographic bone healing in 90.9 % of cases. As regards donor site, there were no differences between the medial femoral donor condyle compared to the contralateral site, due to complete regeneration of donor site bone. MRI investigation showed complete restoration of the donor site with vascularised bone in all patients. Conclusions Our results suggest that the use of bone flaps for the treatment of infected non-unions is an effective procedure, that must be performed after accurate debridement of the non-union site. The corticoperiosteal flap seems to have few morbidities on the donor site and a high percentage of successful bone healing.

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