Objective To analyze and compare the health-related quality of life of adult survivors of acute lymphocytic leukemia and Wilms’ tumor amongst themselves and in relation to healthy participants.Methods Ninety participants aged above 18 years were selected and divided into three groups, each comprising 30 individuals. The Control Group was composed of physically healthy subjects, with no cancer history; and there were two experimental groups: those diagnosed as acute lymphocytic leukemia, and those as Wilms’ Tumor. Quality of life was assessed over the telephone, using the Medical Outcomes Study 36-Item Short Form Health Survey.Results Male survivors presented with better results as compared to female survivors and controls in the Vitality domain, for acute lymphocytic leukemia (p=0.042) and Wilms’ tumor (p=0.013). For acute lymphocytic leukemia survivors, in Social aspects (p=0.031), Mental health (p=0.041), and Emotional aspects (p=0.040), the latter also for survivors of Wilms’ tumor (p=0.040). The best results related to the Functional capacity domain were recorded for the experimental group that had a late diagnosis of acute lymphocytic leukemia. There were significant differences between groups except for the Social and Emotional domains for self-perceived health, with positive responses that characterized their health as good, very good, and excellent.Conclusion Survivors of acute lymphocytic leukemia showed no evidence of relevant impairment of health-related quality of life. The Medical Outcomes Study 36-Item Short Form Health Survey (via telephone) can be a resource to access and evaluate survivors.
ResumoO progressivo sucesso dos esquemas terapêuticos para neoplasias malignas de início na infância permitiu uma melhora significativa da sobrevida dos portadores nas últimas décadas. Contudo, sequelas tardias secundárias à toxicidade destes esquemas devem ser devidamente monitoradas. Dada a relevância da avaliação de aspectos da saúde física, saúde mental, bem como fatores emocionais e sociais dos sobreviventes, avaliou-se a qualidade de vida dos entrevistados por uma abordagem alternativa: o contato telefônico. Aplicou-se o questionário SF-36 (Medical Outcomes Study 36 -Item Short Form Health Survey) validado para a língua portuguesa, em trinta indivíduos, maiores de 18 anos e de ambos os sexos, sobreviventes de leucemia linfocítica aguda, sem terapia antineoplásica há pelo menos cinco anos, em acompanhamento médico no Ambulatório Fora de Terapia do ITACI (grupo experimental), e em trinta indivíduos sadios, pareados por sexo e idade ao grupo experimental (grupo controle). Os sobreviventes analisados apresentaram todos os aspectos do SF-36 superiores ao valor médio. Os resultados médios do total de pontos foram estatisticamente semelhantes ao do grupo controle. O SF-36 proporciona dados valiosos para que a equipe de saúde estabeleça condutas terapêuticas aos sobreviventes. A avaliação por telefone se mostrou importante recurso no acompanhamento ambulatorial desta população. Os sobreviventes de Leucemia Linfocítica Aguda avaliados apresentaram adequados escores de qualidade de vida na atualidade. Palavras-chave:Qualidade vida, Leucemia, Sobreviventes, Telefone. Evaluation of quality of life of survivors of childhood leukemia AbstractThe progressive success of therapeutic plans for malignant neoplasias that started in childhood allowed an important increase in the survival rate of carriers during the last decades. However, late sequelae secondary to the toxicity of such plans shall be duly monitored. Considering the importance of evaluating the aspects of physical and mental health, as well as emotional and social factors of the survivors, the quality of life of the interviewed persons was evaluated by an alternative approach: telephone calls. The SF-36 questionnaire (Medical Outcomes Study 36 -Item Short Form Health Survey), validated for the Portuguese language, was applied to thirty persons with more than 18 years of age and of both sexes, survivors of acute lymphocytic leukemia, without antineoplastic therapy for at least five years, under medical attendance at the Ambulatory outside the ITACI therapy (experimental group), and also to thirty healthy persons, matched by sex and age to the experimental group (control group). Analyzed survivors scored higher in all aspects SF-36 than the average value. The average results of the total points were statistically similar to the control group. SF-36 provides valuable data for the health team to establish therapeutic procedures to survivors. Evaluation by phone became an important resource in the ambulatory follow-up of this population. Survivors of Acute Lymphocyti...
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