Comparative study of quality of life of adult survivors of childhood acute lymphocytic leukemia and Wilms’ tumor

Souza, Clélia Marta Casellato de; Cristófani, Lílian Maria; Cornacchioni, Ana Lucia; Filho, Vicente Odone; Kuczynski, Evelyn

doi:10.1590/s1679-45082015ao3231

Cited by 5 publications

(2 citation statements)

References 9 publications

(44 reference statements)

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“…124,125 More conflicting evidence about vitality was found for patients relative to healthy controls; five studies observed no difference, [125][126][127][128][129] three observed lower vitality, [130][131][132] and three observed higher vitality. [133][134][135] Demographic characteristics followed a similar trend. For example, one study found older patients have more vitality than younger, 121 whereas three studies showed the opposite.…”

Section: Fig 2 Word Cloud Of Constructs and Their Frequency In Inclmentioning

confidence: 61%

Identification of Evidence for Key Positive Psychological Constructs in Pediatric and Adolescent/Young Adult Patients with Cancer: A Scoping Review

Wayant

Manquen

Wendelbo

et al. 2021

Journal of Adolescent and Young Adult Oncology

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Introduction: Children and adolescents/young adults (AYAs) with cancer are a vulnerable population susceptible to numerous late effects, such as fatigue and depression, which may diminish their long-term psychological, physical, spiritual, and emotional health. A well-rounded understanding of how positive psychological constructs affect the quality of care and treatment outcomes is therefore warranted. Methods: We conducted a scoping review of 15 positive psychological constructs in children and AYAs with cancer. The primary research questions were (1) what is known about positive psychological constructs in children and AYAs with cancer; (2) what value is ascribed to these constructs by patients?. Results: Two hundred seventy-six articles were included after database search and screening. These studies were mostly observational or qualitative and conducted in North America. Constructs were often poorly defined, and measurement tools used to gather data were wide ranging. Numerous factors were correlated with increased or decreased expression of certain constructs, but overall themes were difficult to identify. Similarly, patients often spoke of what increased or decreased expression of a construct, with less emphasis on what they implicitly value. Discussion: This scoping review found ample evidence for what increases or decreases expression of positive psychological constructs, but this evidence was observational and often conflicting. In the future, we recommend the development of a core set of psychological outcomes, with definitions and corresponding measurement tools. We further recommend an emphasis on randomized trials to more rigorously study how expression of constructs can be improved and what effect this has on the quality of life.

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Section: Fig 2 Word Cloud Of Constructs and Their Frequency In Inclmentioning

confidence: 61%

Identification of Evidence for Key Positive Psychological Constructs in Pediatric and Adolescent/Young Adult Patients with Cancer: A Scoping Review

Wayant

Manquen

Wendelbo

et al. 2021

Journal of Adolescent and Young Adult Oncology

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“…2 The fact that the emotional function has the lowest score may be related to the discovery and diagnosis of the disease, since, after being aware of the health problem and its severity, even knowing the advances in technologies and treatments, individuals tend to stay worried, insecure, directly affecting their emotional and generating suffering for the patient and their relatives / companions. 14,15 Therefore, it is important to establish Nursing interventions, with the aim of minimizing the alterations in patients' emotional function, through actions such as instillation of hope, support for decision making and counseling; support in coping; family therapy; increase of self-esteem, among others. 16 In addition, it is fundamental in Nursing care, technical and scientific knowledge and psychological support for the control of emotions and relief of suffering.…”

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confidence: 99%

Avaliação da qualidade de vida de pacientes com doença oncohematológica em quimioterapia

Gomes

Coelho

Moura

et al. 2018

Rev enferm UFPE on line.

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RESUMOObjetivo: avaliar a qualidade de vida de pacientes com diagnóstico de doenças oncohematológicas em uso de quimioterapia. Método: estudo quantitativo, transversal, exploratório, descritivo, com pacientes em tratamento quimioterápico, com diagnóstico de doença oncohematológica, em um hospital público filantrópico, utilizando-se, como instrumento para a coleta de dados, o questionário EORTC QLQ-C30 e um formulário para a caracterização do perfil da amostra. A análise dos resultados foi realizada com base no EORTC QLQ-C30 Scoring Manual. Utilizou-se p ≤ 0,05 para a caracterização da análise da amostra e suas variáveis estatisticamente significativas. Resultados: em relação à avaliação da saúde, encontrou-se escore de 69,5 para a classificação de saúde global, caracterizando os participantes com uma qualidade de vida desfavorável. Dentre as funções analisadas, a única avaliada como boa foi a função cognitiva. Em relação aos sintomas e efeitos colaterais, o mais expressivo foi a fadiga, seguida de insônia e falta de apetite, com os respectivos escores, 53,8, 38,3, 31,6. Conclusão: dentre os efeitos colaterais avaliados pelo questionário, os que apresentaram alteração foram poucos, mas deve-se levar em consideração a casuística relativamente pequena. Tais achados servem para subsidiar as ações e práticas dos profissionais de saúde no tratamento aos pacientes com doença oncohematológica. Descritores: Qualidade de Vida; Neoplasias; Leucemia; Linfoma; Enfermagem; Quimioterapia.ABSTRACT Objective: to evaluate the quality of life of patients diagnosed with oncohaematologic diseases using chemotherapy. Method: a quantitative, transversal, exploratory, descriptive study with patients undergoing chemotherapy treatment with a diagnosis of oncohaematological disease in a public philanthropic hospital using the EORTC QLQ-C30 questionnaire as a tool for data collection and a form for characterization of the sample profile. The analysis of the results was performed based on the EORTC QLQ-C30 Scoring Manual. P ≤ 0.05 was used for the characterization of the sample analysis and its statistically significant variables. Results: in relation to the health evaluation, a score of 69.5 was found for the overall health classification, characterizing the participants with an unfavorable quality of life. Among the analyzed functions, the only one evaluated as good, was the cognitive function. Regarding the symptoms and side effects, the most expressive was fatigue, followed by insomnia and lack of appetite, with the respective scores, 53.8, 38.3, 31.6. Conclusion: Among the side effects evaluated by the questionnaire, those that presented alterations were few, but one should take into account the relatively small casuistry. These findings serve to subsidize the actions and practices of health professionals in the treatment of patients with oncohaematological disease. Descriptors: Quality of Life; Neoplasms; Leukemia; Lymphoma; Nursing; Chemotherapy. RESUMEN Objetivo: evaluar la calidad de vida de pacientes con diagnóstico de enfermedades oncohematológicas, en uso de quimioterapia. Método: el estudio cuantitativo, transverso exploratorio, descriptiva, con pacientes en tratamiento de quimioterapia, con diagnóstico de enfermedad oncohematológica en un hospital público filantrópico, donde se utilizó, como instrumento para la recolección de datos, el cuestionario EORTC QLQ-C30 y un formulario para caracterización del perfil de la muestra. El análisis de los resultados se realizó con base en el EORTC QLQ-C30 Scoring Manual. Se utilizó p ≤ 0,05 para la caracterización del análisis de la muestra y sus variables estadísticamente significativas. Resultados: en relación a la evaluación de la salud, se encontró una puntuación de 69,5 para la clasificación de salud global, caracterizando a los participantes con una calidad de vida desfavorable. Entre las funciones analizadas, la única evaluada como buena fue la función cognitiva. En cuanto a los síntomas y efectos colaterales, el más expresivo fue la fatiga, seguida de insomnio y falta de apetito, con las respectivas puntuaciones, 53,8, 38,3, 31,6. Conclusión: entre los efectos colaterales evaluados por el cuestionario, fueron pocos los que presentaron alteración, pero, se debe tener en cuenta la casuística relativamente pequeña. Estos hallazgos sirven para subsidiar las acciones y las prácticas de los profesionales de salud en el tratamiento a los pacientes con enfermedad oncohematológica. Descriptores: Calidad de Vida; Neoplasias; Leucemia; Linfoma; Enfermería; Quimioterapia.

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Burden of Childhood Cancer and the Social and Economic Challenges in Adulthood

Hernádfői,

Koch,

Kói

et al. 2024

JAMA Pediatr

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ImportanceSignificant advancements in pediatric oncology have led to a continuously growing population of survivors. Although extensive research is being conducted on the short-, medium-, and long-term somatic effects, reports on psychosocial reintegration are often conflicting; therefore, there is an urgent need to synthesize the evidence to obtain the clearest understanding and the most comprehensive answer.ObjectiveTo provide a comprehensive review and analysis of the socioeconomic attainment of childhood cancer survivors (CCSs) compared with their unaffected peers.Data SourcesA systematic review and meta-analysis was conducted using data obtained from a comprehensive search of MEDLINE (via PubMed), Embase, and CENTRAL (Cochrane Central Register of Controlled Trials) databases on October 23, 2021; the search was updated until July 31, 2023.Study SelectionEligible articles reported on educational attainment, employment, family formation, quality of life (QoL), or health-risk behavior-related outcomes of CCSs, and compared them with their unaffected peers. Study selection was performed in duplicate by 4 blinded independent coauthors.Data Extraction and SynthesisData extraction was performed in duplicate by 4 independent authors following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Outcome measures were odds ratios (ORs) and mean differences with 95% CIs; data were pooled using a random-effects model.ResultsThe search identified 43 913 articles, 280 of which were eligible for analysis, reporting data on a total of 389 502 survivors. CCSs were less likely to complete higher levels of education (OR, 0.69; 95% CI, 0.40-1.18), had higher odds of health-related unemployment (OR, 2.94; 95% CI, 1.90-4.57), and showed lower rates of marriage (OR, 0.72; 95% CI, 0.63-0.84) and parenthood (OR, 0.60; 95% CI, 0.49-0.74) compared with population-based controls.Conclusion and RelevanceStudy findings suggest that CCSs face several socioeconomic difficulties; as a result, the next goal of pediatric oncology should be to minimize adverse effects, as well as to provide lifelong survivorship support aimed at maximizing social reintegration.

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Comparative study of quality of life of adult survivors of childhood acute lymphocytic leukemia and Wilms’ tumor

Cited by 5 publications

References 9 publications

Identification of Evidence for Key Positive Psychological Constructs in Pediatric and Adolescent/Young Adult Patients with Cancer: A Scoping Review

Identification of Evidence for Key Positive Psychological Constructs in Pediatric and Adolescent/Young Adult Patients with Cancer: A Scoping Review

Avaliação da qualidade de vida de pacientes com doença oncohematológica em quimioterapia

Burden of Childhood Cancer and the Social and Economic Challenges in Adulthood

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