Thermal decomposition of N,N-dimethylcycloijctylamine oxide yielded cis-cycloiictene (go%), indicating that this reactio? OCCUTS by an intramolecular cyclic mechanism, with elimination of the cis-&hydrogen, forming N,N-dimethylhydroxylamine. Decomposition of N,N,N-trimethylcycloijctylammonium hydroxide formed a mixture of cis-and trans-cycloijctenes in 89% yield, which contained 60% of the trans and 40% of the cis isomer according to infrared analysis. The mixture was separated by extraction of the trans isomer with aqueous silver nitrate. Reaction of cis-cyclooctene with osmium tetroxide followed by hydrolysis of the osmic ester formed cis-1,2-cyclooctanediol, while trans-cycloijctene formed trans-l,2-cyclooctanediol. Only the cis isomers of cycloheptene and cyclohexene were formed by the amine oxide elimination and Hofmann exhaustive methylation procedures, the yields of cycloheptene being 92 and 87% and of cyclohexene 83 and 62%, respectively, by the two methods.
Cycloaddition reactions of (R3P) 2M(N3)2 (M = Pd, Pt) with organic nitriles, thiocyanates, isothiocyanates, dimethylacetylenedicarboxylate and carbon disulphide are described; an X-ray analysis of the crystal structure of bis (5-phenyltetrazolato) -bis (triphenylphosphine) palladium (II) is summarised and related to isomerism of the complex in solution.
Alkaloids ok Dichroa febrífuga Lour.
2091The column was washed with water. In all, 30 ml. of eluate was collected and lyophilized.The solid product was triturated with boiling chloroform, and the chloroform solution filtered. Concentration of the filtrate to a small volume gave crystals which were filtered and washed with cold chloroform. The yield of crystalline product, m. p. 75-77°, was 35 mg. Recrystallization of the product from chloroform gave pure dihydrodesoxystreptose, m. p. 78-79°.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.