ABSTRACT. The objective of this study was to evaluate the possible protection of resveratrol against lung injury induced by arsenic trioxide (As 2 O 3 ). Twenty-four healthy Chinese Dragon Li cats of either sex were randomly divided into four groups: control (1 ml/kg physiological saline), As 2 O 3 (1 mg/kg), resveratrol (3 mg/kg) and resveratrol (3 mg/kg) + As 2 O 3 (1 mg/kg). The resveratrol + As 2 O 3 -treated group was given resveratrol 1 hr before As 2 O 3 (1 mg/kg) administration. We found that pretreatment with resveratrol in a clinically comparable dose regimen can reversed the changes in morphological and biochemical parameters induced by As 2 O 3 in the lung. Resveratrol treatment also upregulated the activities of antioxidant enzymes and attenuated As 2 O 3 -induced increases in reactive oxygen species, 8-hydroxydeoxyguanosine and malondialdehyde production in the lung. In addition, resveratrol attenuated the As 2 O 3 -induced reduction in the ratio of reduced glutathione to oxidized glutathione, the content of total glutathione and lung arsenic burden. These findings indicated that resveratrol can provide significant protection against As 2 O 3 -induced oxidative damage.
Emergency language service plays an indispensable role in effective emergency management when dealing with public health crisis like COVID-19. As an emerging research focus in the field of applied linguistics and emergency management, emergency language service has received great attention of scholars from across the world. Drawing on the studies of emergency language service in the existent literature and practices in different contexts, this article firstly reviews a variety of definitions, research subject and range of emergency language service. Then, a comparative analysis of emergency language services in the US, Japan and China is carried out. Finally, the article points out the limitations of studies of emergency language service in the existing literature and puts forward some suggestions for future research.
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