Social media is increasingly cited in plastic surgeon surveys as a reason for undergoing cosmetic procedures, especially non-invasive procedures like onabotulinumtoxinA (Botox) and dermal fillers. We explored trends between social media usage and public interest in cosmetic procedures, as well as how these effects differ by procedure and by specialty (dermatology or plastic surgery). Google Trends was queried for search terms and compared with aggregate user data from Instagram and Facebook. Search terms were the brand names of medications, as these are how the general public knows the medications. Benjamini-Hochberg adjustment for multiple comparisons was used; p<0.02 was considered significant, except for comparisons between specialties, where p<0.01 was significant. The terms dermatologist, Botox, Juvederm, Radiesse, CoolSculpting, Kybella, and facelift have increased in popularity over time, whereas the terms Restylane, liposuction, rhinoplasty, and breast augmentation were decreasing in popularity (p<0.02). No temporal change was observed for Sculptra, Radiesse, blepharoplasty, rhinoplasty and plastic surgeon. Dermatologist (r¼Instagram/r¼Facebook)(0.58/0.54), Botox (0.80/0.47), Juvederm (0.69/0.46) Radiesse (-0.89/-0.40), CoolSculpting (0.81/0.44), and Kybella (0.89/0.43) were associated with Instagram and Facebook user numbers (p<0.02). Blepharoplasty (0.69) and rhinoplasty (0.66) were only associated with Instagram users (p<0.02). Juvederm (r¼0.89) was only associated with dermatologist; Sculptra (r¼0.27), blepharoplasty (r¼0.48), and rhinoplasty (r¼0.66) were only associated with plastic surgeon (p<0.01). Significant correlations were seen for all other search terms between both specialties. Online interest in non-invasive cosmetic procedures is increasing, potentially driven in part by social media. Further, these data suggest that interest in dermatology, compared to other specialties, may especially be increasing due to this phenomenon.