Traditionally, antioxidants are used to scavenge reactive oxygen species (ROS), which are harmful by-products of aerobic metabolism. Inulae Flos, Horsetail, Chinese Leucas, Broomweed and Indian Wikstroemia are five herbal teas commonly consumed by Asians. Our aim was to investigate the hot water extracts of these five herbal teas for their total phenolics/flavonoid contents and antioxidant capacities. Furthermore, with inflammation and hyper-pigmentation considered as two biological processes associated with elevated cellular oxidative stress, Inulae Flos water extract was chosen for further evaluation of its inhibitory effects on the production of LPS-induced inflammatory mediators (such as, TNF-α, IL-6, IL-1β) in RAW 264.7 cells and its anti-tyrosinase activity. Our findings suggest that Inulae Flos might be an alternative source as a potential antioxidant, and a noteworthy inhibitor of production of pro-inflammatory cytokines in a dose-dependent manner. Moreover, it could also serve as a potential natural food additive to prevent browning.
We herein demonstrate a successful synthesis of methylene blue (MB)‐encapsulated liposomal progesterone (LP) with an amplification merit beneficial for analytical applications. Both colormetric and electrochemical immunosensing strips for the leveling of progesterone, a hormone that helps to regulate the menstrual cycle of women, were achieved and characterized. Particular attention was given to the incorporation of an electrochemical screen‐printed electrode toward disposable and deployed diagnostics, enabling the reliable quantification of progesterone in connection to a LOD of 0.83 pg/mL. The novel, simple and specific amplification approach holds the promise to endorse a fast and high‐fidelity diagnostics required for immediate therapeutic attempts.
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