Background:Although exercise has been addressed as an adjuvant treatment for anxiety, depression and cancer-related symptoms, limited studies have evaluated the effectiveness of exercise in patients with lung cancer.Methods:We recruited 116 patients from a medical centre in northern Taiwan, and randomly assigned them to either a walking-exercise group (n=58) or a usual-care group (n=58). We conducted a 12-week exercise programme that comprised home-based, moderate-intensity walking for 40 min per day, 3 days per week, and weekly exercise counselling. The outcome measures included the Hospital Anxiety and Depression Scale and the Taiwanese version of the MD Anderson Symptom Inventory.Results:We analysed the effects of the exercise programme on anxiety, depression and cancer-related symptoms by using a generalised estimating equation method. The exercise group patients exhibited significant improvements in their anxiety levels over time (P=0.009 and 0.006 in the third and sixth months, respectively) and depression (P=0.00006 and 0.004 in the third and sixth months, respectively) than did the usual-care group patients.Conclusions:The home-based walking exercise programme is a feasible and effective intervention method for managing anxiety and depression in lung cancer survivors and can be considered as an essential component of lung cancer rehabilitation.

In recent years, there has been considerable interest in developing blue organic light-emitting devices (OLEDs) with high efficiency, deep-blue color, and long operational lifetime. The deep-blue color is defined arbitrarily as having blue electroluminescent (EL) emission with a Commission Internationale de l'Eclairage y coordinate value (CIE y ) of < 0.15. Such emitters can effectively reduce the power consumption of a full-color OLED and can also be utilized to generate light of other colors by energy cascade to a suitable emissive dopant.It is well known that a guest-host doped emitter system can significantly improve device performance in terms of EL efficiency and emissive color, as well as operational lifetime.[1] Although many blue host materials have been reported, such as anthracene, [2] di(styryl)arylene, [3] tetra(phenyl)pyrene, [4] terfluorenes, [5] and tetra(phenyl)silyl derivatives, [6] blue-doped emitter systems having all the attributes of high EL efficiency, long operational lifetime, and deep-blue color, are rare. [7] This is because designing a fluorescent, deep-blue dopant capable of forming an amorphous glassy state upon thermal evaporation with a much shortened p-conjugation length is a rather daunting task. In addition, finding a deep-blue dopant with a small Stokes shift is essential for efficient Förster energy transfer from the host to dopant molecules, since the energy transfer efficiency is highly dependent on the spectral overlap between the emission of the host and the absorption of the dopant.Recently, we have successfully demonstrated an anthracene-based blue host material, 2-methyl-9,10-di(2-naphthyl)-anthracene (MADN), which possesses a wide energy bandgap of 3.0 eV and can also form a stable thin-film morphology upon thermal evaporation. When doped with a di(styryl)-amine-based blue dopant, p-bis(p-N,N-diphenyl-aminostyryl)benzene (DSA-Ph), it achieved a very high EL efficiency of 9.7 cd A -1 , with a greenish-blue color of CIE x,y (0.16, 0.32) and a long operational lifetime of 46 000 h at a normalized initial brightness of 100 cd m -2 .[8] However, the color saturation of the blue-doped emitter system (DSA-Ph@MADN) is far from adequate for application in full-color OLED displays. On the other hand, the symmetrical di(styryl)amine-based organic molecule is well known to possess a high fluorescent quantum yield, [9] and its emission wavelength (k max = 450-480 nm) is dependent on the p-conjugation length, which encompasses the two strongly donating arylamine moieties. However, the molecular engineering of symmetrical di(styryl)amine-based fluorescent dyes to cause hypsochromic shift has its limitations as both donors are already present as part of the styryl p-conjugation.[10]In this paper, we report a series of novel, deep-blue dopants based on unsymmetrical mono(styryl)amine derivatives, which provide us with a basic structure for color tuning within the 430-450 nm spectral region. We show that when doped in the MADN host as an OLED, some of these deep-blue dopants exhibit a...

Depressive and anxiety disorders were highly prevalent among women who visited an assisted reproduction clinic for a new course of the treatment. Demographic features and a history of previous assisted reproduction treatment were not risk factors for these psychiatric morbidities in the assisted reproduction clinic.

We have developed a highly efficient and stable blue organic electroluminescent (EL) device based on a blue fluorescent styrylamine dopant, p-bis(p-N,N-diphenyl-aminostyryl)benzene, in a morphologically stable high band-gap host material, 2-methyl-9,10-di(2-naphthyl)anthracene, which achieved an EL efficiency of 9.7cd∕A and 5.5lm∕W at 20mA∕cm2 and 5.7 V, with Commission Internationale d’Eclairage coordinates of (x=0.16,y=0.32). The blue-doped device achieved a half-decay lifetime (t1∕2) of 46 000 h at an initial brightness of 100cd∕m2.

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cykao@csie.ntu.edu.tw.

We have synthesized a new green fluorescent dopant C-545P having incorporated five strategically placed "methyl" steric spacers on the julolidyl ring system. C-545P has good thermal properties and photostability, and when fabricated as a dopant in an Alq(3)-hosted OLED device, it shows notable improvement in luminance efficiency and is more resistant to concentration quenching than C-545T, particularly in the doping concentration range between 1 and 2% v/v, while achieving comparable device stability. [structure: see text]