Purpose: This ecological analysis investigates the spatial patterns of the COVID-19 epidemic in the United States in relation to socioeconomic variables that characterize US counties.Methods: Data on confirmed cases and deaths from COVID-19 for 2,814 US counties were obtained from Johns Hopkins University. We used Geographic Information Systems (GIS) to map the spatial aspects of this pandemic and investigate the disparities between metropolitan and nonmetropolitan communities. Multiple regression models were used to explore the contextual risk factors of infections and death across US counties. We included population density, percent of population aged 65+, percent population in poverty, percent minority population, and percent of the uninsured as independent variables. A state-level measure of the percent of the population that has been tested for COVID-19 was used to control for the impact of testing. Findings:The impact of COVID-19 in the United States has been extremely uneven. Although densely populated large cities and their surrounding metropolitan areas are hotspots of the pandemic, it is counterintuitive that incidence and mortality rates in some small cities and nonmetropolitan counties approximate those in epicenters such as New York City. Regression analyses support the hypotheses of positive correlations between COVID-19 incidence and mortality rates and socioeconomic factors including population density, proportions of elderly residents, poverty, and percent population tested.Conclusions: Knowledge about the spatial aspects of the COVID-19 epidemic and its socioeconomic correlates can inform first responders and government efforts. Directives for social distancing and to "shelter-in-place" should continue to stem the spread of COVID-19.

Background The US COVID-19 epidemic impacted counties differently across space and time, though large-scale transmission dynamics are unclear. The study's objective was to group counties with similar trajectories of COVID-19 cases and deaths and identify county-level correlates of the distinct trajectory groups. Methods Daily COVID-19 cases and deaths were obtained from 3141 US counties from January through June 2020. Clusters of epidemic curve trajectories of COVID-19 cases and deaths per 100,000 people were identified with Proc Traj. We utilized polytomous logistic regression to estimate Odds Ratios for trajectory group membership in relation to county-level demographics, socioeconomic factors, school enrollment, employment and lifestyle data. Results Six COVID-19 case trajectory groups and five death trajectory groups were identified. Younger counties, counties with a greater proportion of females, Black and Hispanic populations, and greater employment in private sectors had higher odds of being in worse case and death trajectories. Percentage of counties enrolled in grades 1–8 was associated with earlier-start case trajectories. Counties with more educated adult populations had lower odds of being in worse case trajectories but were generally not associated with worse death trajectories. Counties with higher poverty rates, higher uninsured, and more living in non-family households had lower odds of being in worse case and death trajectories. Counties with higher smoking rates had higher odds of being in worse death trajectory counties. Discussion In the absence of clear guidelines and personal protection, smoking, racial and ethnic groups, younger populations, social, and economic factors were correlated with worse COVID-19 epidemics that may reflect population transmission dynamics during January–June 2020. After vaccination of high-risk individuals, communities with higher proportions of youth, communities of color, smokers, and workers in healthcare, service and goods industries can reduce viral spread by targeting vaccination programs to these populations and increasing access and education on non-pharmaceutical interventions.

Ovarian cancer is the fifth leading cause of female cancer mortality in the U.S. and accounts for five percent of all cancer deaths among women. No environmental risk factors for ovarian cancer have been confirmed. We previously reported that ovarian cancer incidence rates at the state level were significantly correlated with the extent of pulp and paper manufacturing. We evaluated that association using county-level data and advanced geospatial methods. Specifically, we investigated the relationship of spatial patterns of ovarian cancer incidence rates with toxic emissions from pulp and paper facilities using data from the Environmental Protection Agency’s Toxic Release Inventory (TRI). Geospatial analysis identified clusters of counties with high ovarian cancer incidence rates in south-central Iowa, Wisconsin, New York, Pennsylvania, Alabama, and Georgia. A bivariate local indicator of spatial autocorrelation (LISA) analysis confirmed that counties with high ovarian cancer rates were associated with counties with large numbers of pulp and paper mills. Regression analysis of state level data indicated a positive correlation between ovarian cancer and water pollutant emissions. A similar relationship was identified from the analysis of county-level data. These data support a possible role of water-borne pollutants from pulp and paper mills in the etiology of ovarian cancer.

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Background Coal-fired power plants are a major source of air pollution that can impact children’s health. Limited research has explored if proximity to coal-fired power plants contributes to children’s neurobehavioral disorders. Objective This community-based study collected primary data to investigate the relationships of residential proximity to power plants and neurobehavioral problems in children. Methods 235 participants aged 6–14 years who lived within 10 miles of two power plants were recruited. Exposure to particulate matter ≤10 μm (PM 10 ) was measured in children’s homes using personal modular impactors. Neurobehavioral symptoms were assessed using the Child Behavior Checklist (CBCL). Multiple regression models were performed to test the hypothesized associations between proximity/exposure and neurobehavioral symptoms. Geospatial statistical methods were used to map the spatial patterns of exposure and neurobehavioral symptoms. Results A small proportion of the variations of neurobehavioral problems (social problems, affective problems, and anxiety problems) were explained by the regression models in which distance to power plants, traffic proximity, and neighborhood poverty was statistically associated with the neurobehavioral health outcomes. Statistically significant hot spots of participants who had elevated levels of attention deficit hyperactivity disorder, anxiety, and social problems were observed in the vicinity of the two power plants. Significance Results of this study suggest an adverse impact of proximity to power plants on children’s neurobehavioral health. Although coal-fired power plants are being phased out in the US, health concern about exposure from coal ash storage facilities remains. Furthermore, other countries in the world are increasing coal use and generating millions of tons of pollutants and coal ash. Findings from this study can inform public health policies to reduce children’s risk of neurobehavioral symptoms in relation to proximity to power plants.

Although industrial agglomeration and specialization have been studied for more than 100 years, it is still a controversial field. In the era of big data, it is of great significance to study industrial agglomeration and regional specialization by using firm-level data. Based on 3,053,024 pieces of firm-level big data, the spatial evolution and spatial patterns of industrial agglomeration and specialization of 9 major industries in the Yangtze River Delta, China were revealed. Results show that: (1) the degree of industrial agglomeration is highly related to industrial attributes; industries which are directly related to production tend to be geographically concentrated, while industries that serve for production tend to be spatially dispersed; (2) the evolution characteristics and trajectories of industrial agglomeration vary by industries: wholesale and retail trade and real estate are becoming more spatially dispersed; information industries, leasing and commercial services, scientific research and polytechnic services, as well as finance are experiencing continuous spatial agglomeration; construction and manufacturing show a tendency of transfer from spatial agglomeration to spatial dispersion; (3) since 1990, most industries in the Yangtze River Delta have formed distinct spatial patterns of industrial specialization. Most core cities have experienced obvious deindustrialization processes; and high-end industries are clustering to the three biggest core cities of Shanghai, Nanjing, and Hangzhou.

Gunshot detection technology (GDT) has been increasingly adopted by law enforcement agencies to tackle the problem of underreporting of crime via 911 calls for service, which undoubtedly affects the quality of crime mapping and spatial analysis. This article investigates the spatial and temporal patterns of gun violence by comparing data collected from GDT and 911 calls in Louisville, Kentucky. We applied hot spot mapping, near repeat diagnosis, and spatial regression approaches to the analysis of gunshot incidents and their associated neighborhood characteristics. We observed significant discrepancies between GDT data and 911 calls for service, which indicate possible underreporting of firearm discharge in 911 call data. The near repeat analysis suggests an increased risk of gunshots in nearby locations following an initial event. Results of spatial regression models validate the hypothesis of spatial dependence in frequencies of gunshot incidents and crime underreporting across neighborhoods in the study area, both of which are positively associated with proportions of African American residents, who are less likely to report a gunshot. This article adds to a growing body of research on GDT and its benefits for law enforcement activity. Findings from this research not only provide new insights into the spatiotemporal aspects of gun violence in urban areas but also shed light on the issue of underreporting of gun violence.

IntroductionFly ash is a waste product generated from burning coal for electricity. It is comprised of spherical particles ranging in size from 0.1 µm to over 100 µm in diameter that contain trace levels of heavy metals. Large countries such as China and India generate over 100 million tons per year while smaller countries like Italy and France generate 2 to 3 million tons per year. The USA generates over 36 million tons of ash, making it one of the largest industrial waste streams in the nation. Fly ash is stored in landfills and surface impoundments exposing communities to fugitive dust and heavy metals that leach into the groundwater. Limited information exists on the health impact of exposure to fly ash. This protocol represents the first research to assess children’s exposure to coal fly ash and neurobehavioural outcomes.MethodsWe measure indoor exposure to fly ash and heavy metals, and neurobehavioural symptoms in children aged 6 to 14 years old. Using air pollution samplers and lift tape samples, we collect particulate matter ≤10 µm that is analysed for fly ash and heavy metals. Toenails and fingernails are collected to assess body burden for 72 chemical elements. Using the Behavioural Assessment and Research System and the Child Behaviour Checklist, we collect information on neurobehavioural outcomes. Data collection began in September 2015 and will continue until February 2021.Ethics and disseminationThis study was approved by the Institutional Review Boards of the University of Louisville (#14.1069) and the University of Alabama at Birmingham (#300003807). We have collected data from 267 children who live within 10 miles of two power plants. Children are at a greater risk for environmental exposure which justifies the rationale for this study. Results of this study will be distributed at conferences, in peer-reviewed journals and to the participants of the study.