Holographic displays have great potential to realize mixed reality by modulating the wavefront of light in a fundamental manner. As a computational display, holographic displays offer a large degree of freedom, such as focus cue generation and vision correction. However, the limited bandwidth of spatial light modulator imposes an inherent trade-off relationship between the field of view and eye-box size. Thus, we demonstrate the first practical eye-box expansion method for a holographic near-eye display. Instead of providing an intrinsic large exit-pupil, we shift the optical system's exit-pupil to cover the expanded eye-box area with pupil-tracking. For compact implementation, a pupil-shifting holographic optical element (PSHOE) is proposed that can reduce the form factor for exit-pupil shifting. A thorough analysis of the design parameters and display performance are provided. In particular, we provide a comprehensive analysis of the incorporation of the holographic optical element into a holographic display system. The influence of holographic optical elements on the intrinsic exit-pupil and pupil switching is revealed by numerical simulation and Wigner distribution function analysis.

A novel system of optical see-through augmented reality (AR) is proposed by making use of a holographic optical element (HOE) with full-color and lens-array functions. The full-color lens-array HOE provides see-through property with three-dimensional (3D) virtual images, for it functions as a conventional lens array only for Bragg-matched lights. An HOE recording setup was built, and it recorded a 30 mm × 60 mm sized full-color lens-array HOE by using the techniques of spatial multiplexing for large-area recording and wavelength multiplexing for full-color imaging. The experimental results confirm that the suggested full-color lens-array HOE can provide the full-color 3D virtual images in the optical see-through AR system.

Thalamotomy at the ventralis intermedius nucleus for essential tremor is known to cause changes in motor circuitry, but how a focal lesion leads to progressive changes in connectivity is not clear. To understand the mechanisms by which thalamotomy exerts enduring effects on motor circuitry, a quantitative analysis of directed or effective connectivity among motor-related areas is required. We characterized changes in effective connectivity of the motor system following thalamotomy using (spectral) dynamic causal modeling (spDCM) for resting-state fMRI. To differentiate long-lasting treatment effects from transient effects, and to identify symptom-related changes in effective connectivity, we subject longitudinal resting-state fMRI data to spDCM, acquired 1 day prior to, and 1 day, 7 days, and 3 months after thalamotomy using a non-cranium-opening MRI-guided focused ultrasound ablation technique. For the group-level (between subject) analysis of longitudinal (between-session) effects, we introduce a multilevel parametric empirical Bayes (PEB) analysis for spDCM. We found remarkably selective and consistent changes in effective connectivity from the ventrolateral nuclei and the supplementary motor area to the contralateral dentate nucleus after thalamotomy, which may be mediated via a polysynaptic thalamic–cortical–cerebellar motor loop. Crucially, changes in effective connectivity predicted changes in clinical motor-symptom scores after thalamotomy. This study speaks to the efficacy of thalamotomy in regulating the dentate nucleus in the context of treating essential tremor. Furthermore, it illustrates the utility of PEB for group-level analysis of dynamic causal modeling in quantifying longitudinal changes in effective connectivity; i.e., measuring long-term plasticity in human subjects non-invasively.

We propose a see-through additive light field display as a novel type of compressive light field display. We utilize holographic optical elements (HOEs) as transparent additive layers. The HOE layers are almost free from diffraction unlike spatial light modulator layers, which makes this additive light field display more advantageous when modifying the number of layers, thickness, and pixel density compared with conventional compressive displays. Meanwhile, the additive light field display maintains advantages of compressive light field displays. The proposed additive light field display shows bright and full-color volumetric images in high definition. In addition, users can view real-world scenes beyond the displays. Hence, we expect that our method can contribute to the realization of augmented reality. Here, we describe implementation of a prototype additive light field display with two additive layers, evaluate the performance of transparent HOE layers, describe several results of display experiments, discuss the diffraction effect of spatial light modulators, and analyze the ability of the additive light field display to express uncorrelated light fields.

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