Linkage studies have suggested that chromosome 15q13-q14 may harbor a susceptibility locus for schizophrenia. In the current study, the association between a (AC)n dinucleotide repeat polymorphism at D15S118 and schizophrenia was investigated using three independent samples from the Han Chinese population and the Scotland population. In the population-based study, a significant difference was found between the allele frequency distributions in schizophrenia patients and control subjects in the Scottish samples (P = 0.04), but was not replicated in the Chinese samples. In a family-based study, no significant transmission disequilibrium from heterozygous parents to affected offspring was observed. Overall, our results did not support the hypothesis that the (AC)n dinucleotide repeat polymorphism plays a major role in schizophrenia susceptibility, at least in the Chinese population. Further studies are needed to elucidate its role in schizophrenia susceptibility in European population.
The thermal loss from the exhaust flue gas accounts for a large proportion of the thermal loss in the boiler. Under the pressure from the strict emission reduction policy and the rising fuel price, how to improve the fuel utilization ratio and reduce the coal consumption rate is of great significance in the electric industry. Based on the conventional waste heat recovery system, this paper proposes an integrated waste heat recovery system in reference with the German Niederaussem power generation unit. The integrated system improves the fuel utilization ratio and effectively utilize the waste heat with great economic benefits.
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