a b s t r a c tThe standard of reference for confirming COVID-19 relies on microbiological tests such as real-time polymerase chain reaction (RT-PCR) or sequencing. However, these tests might not be available in an emergency setting. Computed tomography (CT) can be used as an important complement for the diagnosis of COVID-19 pneumonia in the current epidemic context. In this review, we present the typical CT features of COVID-19 pneumonia and discuss the main differential diagnosis.

Highlights An algorithm for automatic Covid-19 quantification based on 2D & 3D deep convolutional neural networks is presented. A Covid-19-specific holistic, highly compact multi-omics signature integrating imaging/clinical/ biological data and associated comorbidities for automatic patient staging is presented and evaluated. Short and Long-term prognosis for clinical resources optimization offering alternative/complementary means to facilitate triage for Covid-19 Clinically-relevant quantification and staging tool validated by comparison with clinical experts is reported.