Several drugs were tested, some of them for the first time, against seasickness in military personnel on transport ships on the North Atlantic ocean. All of the drugs were given three fimes a day. Of the new ones tested phenglutarmide, 2.5 mg., and cinnarazine, 7.5 mg., were significantly effective on a single trip. Somewhat less effective were atropine and orphenadrine.Ineffective new drugs were procyclidine, diethazine, cycrimine, caramiphen, pheniprazine, nialamide, phenelzine, benactyzine, and promazine.Cyclizine and meclizine, in doses of 50 mg. three times a day, were again found to be effective.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.