Background Preeclampsia (PE) is one of the highest-risk pregnancies and a complicated condition that occurs in 2% to 8% of pregnancies and is associated with markers of a systemic inflammatory response (SIR). In this study, we aimed to determine the role of these markers in predicting PE. Methodology A total of 300 women with singleton pregnancies and cephalic presentation were included in the study. Normotensive pregnant women (n = 149) who met this criterion were included as the control group Pregnant women who met the inclusion criteria for a diagnosis of preeclampsia (n = 151) were included in the study group. Results The baseline characteristics of the study groups showed no significant difference. The hypertensive group was hospitalized significantly earlier than the control group (p < 0.001). We found significantly higher systolic and diastolic blood pressure values in the PE group than in the other group (p < 0.001). The mean neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and aspartate aminotransferase-to-platelet ratio index (APRI) values at hospitalization did not differ significantly between groups (p = 0.639, p = 0.709, and p = 0.066, respectively). In the receiver operating characteristic analysis curves compared with the control group and PE, none of the parameters could predict PE. Conclusions We found that NLR, PLR, and APRI have no clinical significance in assessing developmental risk and predicting PE.
Objective: This study investigated whether delta-neutrophil index(DNI) and neutrophil/lymphocyte ratio (NLR) values have prognostic significance in wound infections after cesarean section. Material and Methods: In this retrospective study, one hundred and ten patients who developed wound infection and were rehospitalized after cesarean section in a tertiary health center between 2015 and 2019 formed the study group. The same number of patients were in the control group; laboratory tests including DNI, leukocyte count, and percentage of neutrophils were measured 12 hours before surgery (day 0) and 24 hours after surgery (day 1). It was investigated whether these results had predictive value for wound infection. Results: The mean age of patients included in the study was 30.6 (17-55) years, and body mass index was 28.4±3.95 kg/m2. The optimal cut-off value for NLR day 0 was 4.0, with a sensitivity of 80%, a specificity of 38.7%, a positive likelihood ratio of 1.31, a negative likelihood ratio of 0.52. Factors that were effective for the development of wound infection were NLR day 0, 1, and delta. In addition, body mass index was found to be greater than 27, number of cesarean sections was greater than one, and operative time was greater than 50 minutes and less than 30 minutes. Conclusion: We demonstrated that NLR values during cesarean section predicted the development of infections after cesarean section.
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