Selamectin, a novel avermectin compound, was evaluated for its efficacy against naturally occurring infestations of Psoroptes cuniculi and Sarcoptes scabiei. A total of 42 New Zealand rabbits with psoroptic mange and 37 Angora rabbits with sarcoptic mange were used in the present study. On day 0, infested rabbits were treated topically with either selamectin at minimum dose of 6 mg kg(-1) (6-18 mg kg(-1) for New Zealand rabbits, n = 31 and 10-12 mg kg(-1) for Angora rabbits, n = 23) or vehicle only (control groups, n = 11 for New Zealand rabbits, n = 14 for Angora rabbits). The efficacy of selamectin was assessed both clinically and parasitologically by the presence or absence of viable mites. Rabbits were scraped for sarcoptic mites on days 7, 14, 28, 42 and 56 and had otoscopeic and/or microscopic examination for the detection of Psoroptes mites on days 7, 14, 42 and 56. Fisher's exact test was used to assess differences between the vehicle and selamectin treatment in the number of rabbits without mites (cure rates) on each assessment date. It was found that significantly fewer selamectin-treated rabbits had mites detected on skin scrapings (for S. scabiei) or otoscopeic and/or microscopic examination (for P. cuniculi) (P < 0.01) than the vehicle group. Results of the present study suggest that selamectin is effective against naturally infestations of P. cuniculi and S. scabiei in rabbits.

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Background: Ehrlichiosis is a ricketsial disease transmitted by ticks and characterized by reticuloendothelial hyperplasia, fever, generalized lymphadenopathy, splenomegaly and thrombocytopenia. In this study, it was aimed to determine the blood vitamin D and D-dimer levels in dogs with Ehrlichiosis. Methods: The material of this study consisted of 33 dogs of different breeds, ages and both sexes during the period of 2018-2019. In 33 dogs with and without thrombocytopenia with clinical findings, definitive diagnosis and differential diagnosis were made with clinical examination and laboratory tests. All patients were evaluated for Ehrlichiosis with rapid Snap 4DX test kit. In addition, the diagnosis of the disease was made by PCR analysis. Blood D-Dimer levels were determined in control and study groups. Result: D-Dimer levels were significantly higher in the study groups when compared with the control group. Further, when blood D-vitamin levels of control and study groups were compared, it was found that blood D-vitamin levels were significantly lower in dogs with Ehrlichiosis. In conclusion, in this study, D-dimer levels were significantly increased in dogs with ehlichiosis and can be an adjunct biomarker with other clinical, hematologic and laboratory tests. In addition, serum vitamin D levels were found to be low in both active and acute infected patients in dogs previously exposed to the causative agent, which is closely related to the immune system of vitamin D and serum low vitamin D levels may pave the way for the development of ehrlichiosis disease.

Heart frequencies were measured by practical ECG device in six thoroughbred British Horses between the ages were 2-5 years old, which continued the race life. Practical ECG device and smartphone software were found to be successful in getting the records and the device could be used comfortably in race horses.

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Transmissible Venereal Tumor (TVT) is one of the most uncontrolled spreading tumor via mating between dogs observed in both sexes. The clinical findings are less remarkable and are usually located in the caudal part of the penis and may include preputial discharge, licking of the region, dysuria, phimosis or paraphimosis (occasionally). In this study, the incidence of TVT and the relations of tumor with some factors were investigated in 145 male dogs, in Eskiºehir, Turkey. TVT’s diagnosis was based on location of the tumor mass and mainly exfoliative cytological findings. Smears of caudal part of the penis were painted with Giemsa staining method. The cells in the smears were identified as typical transmissible venereal tumor cells, polymorphnuclear leukocytes (PMN), erythrocyte, parabasal, intermediate, nucleated and anuclear superficial cells. In exfoliative cytological examinations, TVT cells were observed in the smears of 17 dogs (11,72 %), but only four of them (2,76 %) had TVT lesions clinically. Thirteen (8,97 %) of dogs had TVT cells but not having TVT lesions . It was found that the ages, weights and breeds of dogs had no effect on the TVT lesions and TVT cells. TVT positive animals were determined to have more erythrocyte and intermediate density than negatives and no association with other cells were found. PMNs were significantly different and high in the TVT cell positive cases compared to the negatives. In dogs with negative TVT cells, parabasal, intermediate, nuclear/anuclear superficial cells were more than those positives. As a result, the male dogs having no lesions could be infected with TVT. Dogs should be examined not only clinically, but also cytologically, to determine whether TVT cells are present. This method can be an easy way to find and treat TVT lesion-free but infected dogs at an early time.