Objectives: Tuberculosis (TB) is a foremost public health problem worldwide. In current years, increasing efforts have been devoted for assessing the health related quality of life of people infected with tuberculosis. The objective of study is to assess the tuberculosis treatment compliance in smokers and non-smokers in Bengaluru region. Methods: TB patients meeting the inclusion criteria had enrolled for the study. The frequency and percentage of each parameter such as occupation, education, patient type, diagnosis, treatment, duration of hospitalization, abdominal pain and dizziness were evaluated. Results: After the treatment of 3month, out of 300 patients 24 patients of smokers and 12 patients of non-smokers were suffered from abdominal pain and 8 patients of smokers and 24 patients of non-smokers were suffered from dizziness. The duration of hospitalization in smokers was 383 days whereas in non-smokers it was 115 days. Maximum numbers of TB patients were found to be unemployed in smokers than in non-smokers patients.In smoker group 82 patients have gotCAT-1 and 68 patients have gotCAT-2 treatment but in non-smoker group 129 patients were taken CAT-1 and 21 patients were received CAT-2 treatment.
Conclusion:The percentage of abdominal pain and dizziness, duration of hospitalization was seen more in smokers as compared to non-smokers. Percentage of education, occupation level and salary was found to be less in smokers than the non-smokers as it causes low hygienic and easy susceptibility to TB infection. Final diagnosis suggests that pulmonary TB was seen in smokers and extra pulmonary TB in non-smokers patients.
BackgroundPneumonia continues to be a leading cause of death globally; however, in >50% of cases, an etiological agent is not identified. We describe the use of a multi-pathogen platform, TaqMan array card (TAC) real-time PCR, for the detection of pathogens in patients hospitalized with severe respiratory illness (SRI).MethodsWe conducted prospective hospital-based surveillance for SRI among patients at two sentinel sites in South Africa between January and December 2017. Patients were included in this study if a blood specimen and at least one respiratory specimen (naso- and oro-pharyngeal (NP/OP) swabs and/or sputum) were available for testing. We tested respiratory specimens for 21 respiratory pathogens and blood samples for nine bacteria using TAC. Pathogen detection was compared by age group and HIV status using the chi-squared test.ResultsDuring 2017, 956 patients were enrolled in SRI surveillance, and of these, 637 (67%) patients were included in this study (637 blood, 487 NP/OP and 411 sputum specimens tested). At least one pathogen was detected in 83% (527/637) of patients. Common pathogens detected included H. influenzae (225/637; 35%), S. pneumoniae (224/637; 35%), rhinovirus (144/637; 23%), S. aureus (129/637; 20%), K. pneumoniae (85/637; 13%), M. tuberculosis (75/637; 12%), and respiratory syncytial virus (57/637; 9%). Multiple pathogens (≥2) were co-detected in 57% (364/637) of patients.ConclusionWhile use of a multi-pathogen platform was useful in the detection of a pathogen in the majority of the patients, pathogen co-detections were common and would need clinical assessment for usefulness in individual-level treatment and management decisions.
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