2022
DOI: 10.1016/j.ijid.2022.06.011
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Pathogens detected using a syndromic molecular diagnostic platform in patients hospitalized with severe respiratory illness in South Africa in 2017

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“…The higher positivity rate from previous studies other than ours might be owing to a single densely populated slummy study site in Kenya and the use of combined oropharyngeal and nasopharyngeal specimen testing and a shorter date of disease onset during study participant enrollment in Morocco. The lower positivity rate of our study finding compared with the 24.4% of South Africa [24] might be owing to the study participant characteristics, which included HIV-positive cases and the majority of them were children under 1 year of age, in whom underlying health conditions and age play a role in RSV infection risk in many other studies. Moreover, the shorter date of sample collection from date disease onset and the very young age (>3 months) of study participants, the majority of whom have underlying health conditions, included in the study from India might also be a reason for the higher positivity rate than ours.…”
Section: Discussioncontrasting
confidence: 62%
“…The higher positivity rate from previous studies other than ours might be owing to a single densely populated slummy study site in Kenya and the use of combined oropharyngeal and nasopharyngeal specimen testing and a shorter date of disease onset during study participant enrollment in Morocco. The lower positivity rate of our study finding compared with the 24.4% of South Africa [24] might be owing to the study participant characteristics, which included HIV-positive cases and the majority of them were children under 1 year of age, in whom underlying health conditions and age play a role in RSV infection risk in many other studies. Moreover, the shorter date of sample collection from date disease onset and the very young age (>3 months) of study participants, the majority of whom have underlying health conditions, included in the study from India might also be a reason for the higher positivity rate than ours.…”
Section: Discussioncontrasting
confidence: 62%