Multiple brain metastases from ovarian carcinoma are rare. CT findings are reported in a case treated with whole brain radiation therapy and chemotherapy. Radiological complete-calcified brain metastases following treatment and long morphological changes occurred. Delayed neurological findings in relation to treatment are considered. Long survival with unmodified calcified lesions may suggest a stabilization of CNS disease.

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As radiotherapy practice and processes become more complex, the need to assure quality control becomes ever greater. At present, no international consensus exists with regards to the optimal quality control indicators for radiotherapy; moreover, few clinical audits have been conducted in the field of radiotherapy. The present article describes the aims and current status of the international IROCA "Improving Radiation Oncology Through Clinical Audits" project. The project has several important aims, including the selection of key quality indicators, the design and implementation of an international audit, and the harmonization of key aspects of radiotherapy processes among participating institutions. The primary aim is to improve the processes that directly impact clinical outcomes for patients. The experience gained from this initiative may serve as the basis for an internationally accepted clinical audit model for radiotherapy.

este artículo, la autora revisa y examina las aportaciones bibliográficas sobre comunicación científica que se han realizado desde distintas áreas de conocimiento, en las últimas décadas en nuestro país. Así pues, muestra las debilidades presentes en los escasos estudios sobre el tratamiento informativo de la ciencia y la tecnología, realizados desde las facultades de Ciencias de la Información y la fortaleza de los trabajos abordados desde las facultades de Ciencias Experimentales donde hay abierta una línea de investigación sobre historia del periodismo científico.

Granulocytic sarcomas are rare tumors that can present in innumerous locations; thus there is very little clinical experience with these cases. Therefore there is no consensus on which is the best treatment for patients with this malignancy. The authors present a case of a female with a granulocytic sarcoma of the breast and review the literature for the role of radiotherapy in the management of this clinical entity.

La presente investigación tiene como objetivo valorar y estudiar el tratamiento de las terapias no convencionales, complementarias, alternativas o integrativas a través de los programas electorales de las Elecciones Generales de 2015 de cinco partidos políticos: Ciudadanos, Podemos, PP, PSOE y Unidad Popular. Asimismo, se analizan los tuits publicados por sus cabezas de lista, durante la campaña electoral. Para abordar la investigación, hemos recurrido a dos métodos de recogida de datos y su posterior evaluación. Para estudiar los programas electorales, hemos utilizado una ficha de vaciado de análisis de contenido. Para analizar los tuits, hemos empleado el software T-LAB 9.1. de análisis de corpus lingüístico. Los principales resultados de la investigación muestran que se hacen muy pocas referencias a este tipo de terapias. En Unidad Popular y Ciudadanos proponen que no formen parte de la cartera de servicios del SNS, mientras que el PSOE propone regularlas para aquellas personas que deseen utilizarlas.

Resumen-El presente trabajo ofrece una validez de constructo de un cuestionario sobre percepciones y creencias de epidemia. El instrumento a utilizar se apoya con el uso del cine para favorecer aprendizaje significativo y fomentar aprendizaje a lo largo de la vida. Se aprecian dificultades en aspectos de comunicación y ética frente a una epidemia. Los resultados obtenidos en este piloto permiten afirmar que esta experiencia sirve para crear y desarrollar competencias profesionales de tipo comunicativa y pensamiento crítico. Se identificaron situaciones éticas en sucesos complejos que afectan el desempeño de su actividad profesional Palabras clave: medios de comunicación, epidemias, aprendizaje, educación basada en competencias Abstract-The present work offers a construct validity of a questionnaire about perceptions and beliefs of epidemic. The instrument to be used is supported by the use of cinema to promote meaningful learning and to encourage lifelong learning. There are difficulties in communication and ethics in the face of an epidemic. The results obtained in this pilot allow to affirm that this experience serves to create and to develop professional competences of type communicative and critical thinking. Ethical situations were identified in complex events that affect the performance of their professional activity

Novel mechanistic insights are discussed herein that link a single, nontoxic, low-dose radiotherapy (LDRT) treatment (0.5-1.0 Gy) to (1) beneficial subcellular effects mediated by the activation of nuclear factor erythroid 2-related transcription factor (Nrf2) and to (2) favorable clinical outcomes for COVID-19 pneumonia patients displaying symptoms of acute respiratory distress syndrome (ARDS). We posit that the favorable clinical outcomes following LDRT result from potent Nrf2-mediated antioxidant responses that rebalance the oxidatively skewed redox states of immunological cells, driving them toward antiinflammatory phenotypes. Activation of Nrf2 by ionizing radiation is highly dose dependent and conforms to the features of a biphasic (hormetic) dose-response. At the cellular and subcellular levels, hormetic doses of <1.0 Gy induce polarization shifts in the predominant population of lung macrophages, from an M1 pro-inflammatory to an M2 anti-inflammatory phenotype. Together, the Nrf2-mediated antioxidant responses and the subsequent shifts to anti-inflammatory phenotypes have the capacity to suppress cytokine storms, resolve inflammation, promote tissue repair, and prevent COVID-19-related mortality. Given these mechanistic considerations-and the historical clinical success of LDRT early in the 20th century-we opine that LDRT should be regarded as safe and effective for use at almost any stage of COVID-19 infection. In theory, however, optimal life-saving potential is thought to occur when LDRT is applied prior to the cytokine storms and before the patients are placed on mechanical oxygen ventilators. The administration of LDRT either as an intervention of last resort or too early in the disease progression may be far less effective in saving the lives of ARDS patients.