En este documento se explica desempeño de una aplicación de realidad virtual inmersiva, de desarrollo propio (Crality 0.1), a los métodos de enseñanza de la composición arquitectónica, ayudando a que la educación afronte los retos que implica la enseñanza a las nuevas generaciones de estudiantes, al mismo tiempo permite que la creatividad como elemento fundamental en este proceso se potencie con el mínimo de obstáculos posibles. Se toma como marco teórico e indicadores sobre la creatividad los procesos de composición en el diseño arquitectónico y principios generadores de la forma. La evaluación se lleva cabo mediante el análisis de la forma de aprendizaje de la composición arquitectónica a través de la aplicación de realidad virtual comparada con un modelo de control manual de materialidad física. Los resultados condujeron a concluir la eficacia en el proceso de aprendizaje del acompañamiento de la realidad virtual, ya que reduce tiempos de ejecución, disminución del uso de material y una mayor afinidad con los procesos cognitivos de las nuevas generaciones. En aquest document s'explica acompliment d'una aplicació de realitat virtual immersiva, de desenvolupament propi (Crality 0.1), als mètodes d'ensenyament de la composició arquitectònica, ajudant a que l'educació afronti els reptes que implica l'ensenyament a les noves generacions d'estudiants , a el mateix temps permet que la creativitat com a element fonamental en aquest procés es potenciï amb el mínim d'obstacles possibles. Es pren com a marc teòric i indicadors sobre la creativitat els processos de composició en el disseny arquitectònic i principis generadors de la forma. L'avaluació es porta terme mitjançant l'anàlisi de la forma d'aprenentatge de la composició arquitectònica a través de l'aplicació de realitat virtual comparada amb un model de control manual de materialitat física. Els resultats van conduir a concloure l'eficàcia en el procés d'aprenentatge de l'acompanyament de la realitat virtual, ja que redueix temps d'execució, disminució de l'ús de material i una major afinitat amb els processos cognitius de les noves generacions. This paper explains the performance of a self-developed immersive virtual reality application (Crality 0.1) to the teaching methods of architectural composition, helping education to face the challenges of teaching new generations of students, while at the same time allowing creativity as a fundamental element in this process to be enhanced with the minimum possible obstacles. The theoretical framework and indicators of creativity are taken as a framework for the processes of composition in architectural design and the principles that generate form. The evaluation is carried out by analysing the way of learning architectural composition through the application of virtual reality compared to a manual control model of physical materiality. The results led to conclude the effectiveness in the learning process of the virtual reality accompaniment, since it reduces execution times, reduces the use of material, and a greater affinity with the cognitive processes of the new generations.
Background and Aim: Infectious bovine keratoconjunctivitis is the most crucial ophthalmic disease among ruminants worldwide. Moraxella is the bacteria generally associated with this disease and leads to keratitis, conjunctivitis, corneal ulcers, or blindness. Platelet-rich plasma (PRP) effects in corneal ulcers and different ocular superficial diseases in animals and humans are beneficial and enhance rapid healing and improvement, but the effects in infectious keratoconjunctivitis in ruminants are uncertain. This study aimed to examine the effect of PRP on re-epithelization, corneal tissue, clinical signs, and matrix metalloproteinase (MMP) expression in sheep with infectious keratoconjunctivitis. Materials and Methods: Eighteen sheep were divided into three groups and subjected to a disease-induction experiment. Group 1 (G1) was administered 1.0 mL PRP subconjunctivally, Group 2 (G2) was administered 1.0 mL PRP subconjunctivally and 50 μL gentamicin drops, and the control group (CG) was administered 50 μL saline solution topically every 12 h. Clinical ophthalmologic examination, fluorescein staining, and photography were carried out. Ulcerated areas were measured employing J-Image software. Five and eleven days following the procedure, half of the animals from each group were euthanized, and their corneas were evaluated by histopathology and zymography. Results: Control Group and G2 epithelialized more rapidly. The CG exhibited fewer clinical signs of ocular disease. In histopathological analysis, in G2, alterations were observed only in the epithelium. The CG and G1 exhibited alterations in the epithelium, stroma, and Descemet’s membrane. In zymography, a decline in MMP-2 expression in the animals treated with PRP was detected. Matrix metalloproteinase-9 was significantly expressed in the animals treated with PRP monotherapy, whereas PRP + gentamicin and CG caused a decrease. Conclusion: Platelet-rich plasma alone did not demonstrate any beneficial effect on re-epithelialization, a decline in clinical signs, tissue alterations, and expression of metalloproteinases. Platelet-rich plasma combined with gentamicin was capable of suppressing MMPs, primarily MMP-9, but do not display positive effects in re-epithelization, reduction of clinical signs, or tissue effects. These outcomes are similar to those discovered in untreated animals, so the use of PRP in patients with infectious keratoconjunctivitis does not offer greater benefits in sheep. Additional research is required to validate the results of PRP use in natural disease presentation. Keywords: corneal ulcers, experimental model, matrix metalloproteinase, Moraxella spp., pinkeye, platelet-rich plasma.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.