Background: COVID-19 commonly presents with upper respiratory symptoms; however, studies have shown that SARS-CoV-2 infection affects multiple organ systems. Here, we review the pathophysiology and imaging characteristics of SARS-CoV-2 infection in organ systems throughout the body and explore commonalities.
Objective: Familiarity with the underlying pathophysiology and imaging characteristics is essential for the radiologist to recognize these findings in patients with COVID-19 infection. Though pulmonary findings are the most prevalent presentation, COVID-19 may have multiple manifestations and recognition of the extrapulmonary manifestations is especially important because of the potential serious and long-term effects of COVID-19 on multiple organ systems.
sufficient for the diagnosis of air trapping. Often there is no evidence of mosaic attenuation on inspiratory CT scans when subsequent expiratory images demonstrate air trapping [1-3]. Limited sensitivity for mosaic attenuation on inspiratory CT scans supports the use of expiratory imaging when air trapping is suspected [4-7].
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