The objective of this study was to determine the distribution of staphylococcal cassette chromosome mec (SCCmec) elements in meticillin-resistant coagulase-negative staphylococci (MR-CoNS) isolated from a tertiary-care hospital in Mexico and to examine the relationship to drug resistance. Fifty selected MR-CoNS isolates collected from catheters (n515), blood (n515), bone (n59), bronchial lavage (n52) and urine (n52) and one isolate each from an abscess, cerebrospinal fluid, eye, pleural effusion, synovial fluid, tracheal aspirate and wound secretion were examined. Susceptibility testing was performed by the broth microdilution method. SCCmec types were determined by multiplex PCR and PFGE was carried out as described previously for Staphylococcus aureus. Among the MR-CoNS strains studied, the most frequently isolated species were Staphylococcus epidermidis (n526) and Staphylococcus haemolyticus (n513). Staphylococcus cohnii (n55), Staphylococcus hominis (n53), Staphylococcus sciuri (n51), Staphylococcus pasteuri (n51) and the recently described species Staphylococcus pettenkoferi (n51) were also identified. The most frequent MR-CoNS genotype identified was SCCmec type IVa in S. epidermidis isolates, which also showed a high diversity in their PFGE patterns. A clone was found that amplified both SCCmec III and V elements in five isolates examined. The single MR S. pettenkoferi isolate harboured SCCmec type IVd and the single MR S. pasteuri isolate harboured SCCmec type I. The carriage of SCCmec type III was associated with resistance or intermediate resistance to meropenem (P ,0.05). These results confirm the high prevalence of S. epidermidis SCCmec IVa and the high genetic diversity among MR-CoNS strains. As far as is known, this is the first report describing the newly identified S. pettenkoferi possessing SCCmec IVd and S. pasteuri harbouring SCCmec type I. MR-CoNS harbouring SCCmec type III were found to be more resistant to meropenem.
The North Western Sahara Aquifer System stands out as one of the water scarcest regions in the world. Moreover, in recent decades agriculture activity has grown exacerbating the pressure on groundwater resources and pumping energy requirements. In this study, a water-energy-food Nexus approach was used to assess the effect of capturing, treating and reusing wastewater for irrigation. GIS-based tools were used to capture the systems spatial dimension, enabling to match wastewater supply and water demand points, identify demand hotspots and evaluate techno-economically viable wastewater treatment options. Moreover, the minimum energy requirements for brackish water desalination were estimated. Seven domestic wastewater treatment technologies and one irrigation tailwater treatment technology were evaluated, making use of a levelized cost of Water methodology to identify the least-cost system. Four scenarios were constructed based on water-consumption behaviour of farmers towards changes in irrigation water pricing. The identified least-cost wastewater treatment technologies showed clear trade-offs, as different technologies were more cost-effective depending on treatment capacity requirements of the spatially distributed agglomerations. The reuse of treated wastewater/tailwater in agricultural irrigation, showed improvement of groundwater stress, reducing on about 49% water abstractions and groundwater stress levels in the best case scenario. However, groundwater stress still fell on the extremely high category, highlighting the critical condition of the aquifer. Furthermore, reuse of wastewater/tailwater decreased dependency on groundwater pumping and the overall energy-for-water requirements, reducing by about 15% the total energy requirements in the best case scenario. However, to effectively preserve water resources and act holistically towards the sustainable development agenda, measures as better water pricing mechanisms, management strategies to improve water productivity and adoption of more efficient irrigation schemes may be needed.
The North Western Sahara Aquifer System (NWSAS) is a vital groundwater source in a notably water-scarce region. However, impetuous agricultural expansion and poor resource management (e.g., over-irrigation, inefficient techniques) over the past decades have raised a number of challenges. In this exploratory study, we introduce an open access GIS-based model to help answer selected timely questions related to the agriculture, water and energy nexus in the region. First, the model uses spatial and tabular data to identify the location and extent of irrigated cropland. Then, it employs spatially explicit climatic datasets and mathematical formulation to estimate water and electricity requirements for groundwater irrigation in all identified locations. Finally, it evaluates selected supply options to meet the electricity demand and suggests the least-cost configuration in each location. Results indicate that full irrigation in the basin requires ~3.25 billion million m3 per year. This translates to ~730 GWh of electricity. Fossil fuels do provide the least-cost electricity supply option due to lower capital and subsidized operating costs. Hence, to improve the competitiveness of renewable technologies (RT) (i.e., solar), a support scheme to drop the capital cost of RTs is critically needed. Finally, moving towards drip irrigation can lead to ~47% of water abstraction savings in the NWSAS area.
Resumen Este trabajo examina el efecto conjunto de la democracia y libertad económica sobre la corrupción. Para ello, se utilizan las bases de datos de 160 países de los años 2010 - 2016, considerando varias fuentes de información para un conjunto de variables económicas, culturales, históricas e institucionales. Las pesquisas señalan que el efecto conjunto de los niveles de libertad económica y democracia es importante para combatir la corrupción. Por lo tanto, las políticas más eficaces para los países objeto de estudio, serán aquellas enfocadas al derecho fundamental que tienen los seres humanos para controlar el fruto de su trabajo, englobando de manera integral las libertades y derechos de producción, distribución o consumo de bienes y servicios.
Background: In Colombia, public policy has encouraged hospital efficiency and sustainability since 1993, when its health system underwent a profound change with the Law 100. Method: We estimate the efficiency and productivity of Colombian public hospitals using the Luenberger productivity indicator. This less restrictive indicator allows for a disaggregated regional analysis and does not overestimate the change in productivity when compared to other measures. It was made an empirical application to a sample of 260 hospitals during the 2004-2015 period. Results: The results show a productivity decline for Colombian public hospitals, explained mainly by the decrease in technological change as a result of low investment in technology. In fact, one out of every eighty-seven hospitals reached an improvement in efficiency and technological change simultaneously, while, one out of every two experienced the opposite. On average, hospitals in all regions showed a productivity decrease, in particular those in the Eastern region, an area that accounted, with the Central region, three-fifths of the overall decline. Discussion and conclusion: The efficiency and productivity that was sought to be achieved through the profound change in the health system were insufficient. Thus, governmental measures should: encourage managers to modernize their administrative and organizational factors, promote the development of technology and research in health by greater investments, and foster complementary and non-competitive relationships among hospitals.
Universal clean cooking is a key target under Sustainable Development Goal (SDG) 7, with implications for several other SDGs, such as good health, gender equality and climate. Yet, 2.4 billion people globally still lack access to clean cooking. The situation is especially dire in sub-Saharan Africa (SSA), where only 17% use clean options. We develop OnStove, an open-source spatial tool comparing the relative potential of different cookstoves on the basis of their costs and benefits, and apply it to SSA. Our results suggest a severe market failure as the currently most used solution, traditional biomass, produces the lowest social net-benefits nearly everywhere in SSA. Correcting this failure, which stems from multiple market and behavioural obstacles, would deliver significant health, time and emission benefits but requires identification and promotion of policies to transform cooking energy use. Spatial mapping offers a more nuanced understanding of the costs needed to deliver cleaner cooking transitions than was previously possible, which is useful for improved targeting of intervention strategies.
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