WHO declared COVID-19 infection as a pandemic since 2020. A rapid noninvasive examination is needed for screening and diagnostic. Exhaled Volatile Organic Compound (VOC) is a sample directly connected to the affected organ, which is the lung, and can be measured as an endogenous volatile marker resulted from oxidative stress. This study aims to analyze differences in VOC concentration in COVID-19 patients with pneumonia and without pneumonia. This Case Control Study used 93 confirmed case samples of COVID-19 and 42 healthy subject. Demographic and clinical data taken from anamnesis and/or medical records. VOC’s data of respiratory track are taken through the exhalation air in a bag and analyzed with breathanalyzer. Statistical analysis was conducted using Mann-Whitney test. In the analysis of confirmed samples of COVID-19 between pneumonia and without pneumonia, co components were found to affect the incidence of pneumonia in confirmed samples of COVID-19 (p=0.003). This conclusion is Components of CO in confirmed COVID-19 have a meaningful effect on an event of pneumonia.
esensial baik kualitas maupun kuantitas sangat penting untuk pertumbuhan normal. Salah satu parameter perkembangan anak adalah perkembangan motorik kasar yaitu aspek yang berhubungan dengan pergerakan dan sikap tubuh yang melibatkan otot-otot besar. Tujuan: Mengetahui hubungan antara status gizi dengan perkembangan motorik kasar anak usia bayi dan balita (0-59 bulan) di Puskesmas Pandanwangi Malang. Metode: Analitik observasional dengan pendekatan cross sectional. Pengambilan sampel secara cluster sampling dengan populasi 148 responden. Jumlah sampel 122 responden. Dianalisa dengan uji chi square. Hasil Penelitian: 29,5% responden mengalami keterlambatan perkembangan motorik kasar yang terdiri dari 3,3% responden sangat kurus, 7,4% responden kurus,15,6% responden normal dan 3,3% anak gemuk, dengan nilai p sebesar 0,000 dan α =0,05.Kesimpulan: Terdapat hubungan yang sangat signifikan antara status gizi dengan perkembangan motorik kasar. ABSTRACT The correlation between Nutritional Status and Gross Motoric Developmenton Under Five's Children (0-59 months) in Pandanwangi Health Center Malang. Backgrounds: Lack of essential food,either in quality or quantity is very important for normal growth. One of the parameter in child development is the gross motoric development, which is an aspect that is related to the movement and body posture that involve large muscles. Objectives: To study the correlation between nutritional status and gross motoric development on under five's children (0-59 months) in Pandanwangi Health
To describe Sequential Organ Failure Assessment (SOFA) Score parameters which have a great impact in the condition of sepsis in Corona Virus Disease-19 (COVID-19) patients and comorbidities that aggravate the patient's condition, we conducted a prospective cohort study in adult patients with sepsis and confirmed COVID-19 cases. We conducted a prospective cohort study in confirmed COVID-19 patients with sepsis who were admitted at Saiful Anwar Hospital Malang at March 10th–April 21st 2020. Diagnosis of sepsis is based on the Surviving Sepsis Campaign-III criteria. We found 6 COVID-19 confirmed patients with sepsis. There is an increased respiratory parameter in SOFA Score in these patients. Therefore, respiratory parameter of the SOFA score has a great impact in determining sepsis condition among confirmed COVID-19 patients. Keywords: COVID-19, Sepsis, SOFA Score
Introduction: Asthma is heterogenous disease characterized by chronic airway inflammation. COVID-19 pandemic has an impact on health services where telemedicine could provide alternative method to evaluate patient’s condition, reduce risk of infection and disease transmission. The aim of this study is to analysis knowledge, asthma symptoms control and risk factors among the asthmatic patients via telemedicine Methods: Data was obtained from telemedicine of 28 asthmatic patients in the context of community services. Inclusion criteria is stable asthmatic patients who conducted medical interview via videocall application. Cross sectional data were taken including demographic, knowledge of subjects, profile of subjects, and assessment of asthma symptoms control and assessment of poor outcomes. Data were analyzed descriptively and variables were analyzed using chi-square. Results: Subjects consisted of 28 stable asthmatic patients. The average of asthma onset was 17.96 years old. Clinically profile showed that 67.86% subjects were not routinely controlled, 64.29% had never performed pulmonary function test, 67.86% subjects didn’t know the level of asthma control symptoms. Evaluation based on GINA symptoms control only 39.29% were in good control condition, 35.71% were partially controlled and 25% in uncontrolled condition. Use of inhaler device recently or previously prescribed on 67.86% subjects. Evaluation of knowledge about asthma still unsatisfactory, 67.86% subjects didn’t know about their modifiable risk factors, 96.43% didn’t know about written action asthma plan, 60.71% didn’t know about asthma exercise. Self-medication was associated with poor asthma control (p=0,036) and knowledge about modifiable risk factors related to asthma symptoms control (p=0,041). Conclusion: Self-medication is related to uncontrolled asthma and knowledge of modifiable factors is related asthma symptoms control. It is important to educate the patient about the modifiable risk factors of asthma and how to manage it. Patient knowledge about their disease is still lacking, and there is a need for ongoing education to achieve good asthma control. Alternative intervention through telemedicine especially for continuing education and may therapeutic strategies can be performed as an effort to obtain well controlled asthma in community. Telemedicine, particularly in asthma management may benefit as an alternative approach of healthcare service in the context of pandemic era.
Background/aim: The analysis of VOCs through respiration has been used for biomarker analysis for the detection of novel coronaviruses and has found mainly six VOCs by breath analysis by GC-IMS are ethanol, octane, acetone, cluster mixture of acetone/butanone and methanol. Previous research found exhaled methanol concentrations were lower in COVID-19 patients. The aim of this study was to analyze differences in VOC concentration in Covid-19 patients with healthy people. Methods: This Case Control study used 93 confirmed case samples of Covid-19 and 42 healthy people. Demographic and clinical data taken from anamnesis and/or medical records. VOC’s data of respiratory track are taken through the exhalation air in a bag and analyzed with breath analyzer. Statistical analysis was conducted using Mann-Whitney test. Results: VOC compound measured include CO2, C7H8, CH2O, NH4, TVOC, NO2, PM1.0, CO, NH3, and Acetone. Analysis between Covid-19 patients and healthy people showed significant differences in all VOC components CO2 (p=0,000), C7H8 (p=0,000), CH2O (p=0,000), NH4 (p=0,001), TVOC (p=0,000), NO2 (p=0,000), PM1.0 (p=0,000), CO (p=0,000), NH3 (P=0,000), Acetone (p=001). Logistic regression analysis was obtained no meaningful influence on each component of the VOC with covid/healthy people conditions of patients with components CO2 (p=1,000), C7H8 (p=1,000), CH2O (p=0,999), NH4 (p=1,000), TVOC (p=1,000), NO2 (p=1,000), PM1.0 (p=0,999), CO (p=0,999), NH3 (P=0,999), Acetone (p=1,000). Conclusion: There is a significant difference between the VOC results of confirmed COVID 19 patients and healthy people Keywords: breath analyzer, coronaviruses, COVID-19, healthy people, volatile organic component
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