A series of lipophilic and hydrophilic fac tricarbonyl rhenium bisimine complexes have been prepared, their membrane-permeabilities explored in liposomes and their potential for application in fluorescence microscopy cell imaging demonstrated in the first application of MLCT-fluorescent rhenium complexes in cell imaging.
These findings add to accumulating evidence for a possible role of zinc in ADHD, even for middle-class Americans, and, for the first time, suggest a special relationship to inattentive symptoms. They do not establish either that zinc deficiency causes ADHD nor that ADHD should be treated with zinc. Hypothesis-testing clinical trials are needed.
The medium-term outcomes were good for the participants in both treatment groups, perhaps because they were selected for good response. When nonresponders were included in ITT analyses, there was some indication that Augmented surpassed Basic treatment.
Connected autonomous vehicles (CAVs) represent an exciting opportunity for wider access to mobility; especially for individuals unable to drive manual vehicles. Interaction with CAVs will be through human-machine interfaces (HMIs) providing journey-related and other information with some interactivity. These should be designed with potential users as part of a co-design process to maximize acceptance, engagement, and trust. This paper presents an emerging framework to inform the design of in-vehicle CAV HMIs with a focus on older adults (70-years+). These could be amongst early adopters of CAVs and tend to have the highest level of cognitive, sensory, and physical impairments. Whilst there are numerous principles on HMI design for older adults there are fewer on HMIs for AVs, and a need for research on CAV HMI design principles for older adults. Our emerging framework is novel and important for designers of CAV HMIs for older adults and other potential users.
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