THE object of this paper is to report a study of the physiological state of four normal male subjects during exercise on a stationary bicycle. In the interpretation of the data obtained consideration has been given to the character and severity of the work done by a given subject. An analysis of the results appears to show some of the adaptations which the organism as a whole may make as a result of physical training. The variations found in the different subjects are sufficiently great to ilidicate the range of individual reactions to the same type of muscular exercise, and for this reason throw some light on observations made in the past by others in which apparently contradictory results have been reported.All of the subjects of this study were known to be in good health. One subject, DeMar, the Marathon runner, has maintained a state of physical training continuously for approximately 20 years. This athlete runs ten miles or more daily with few exceptions throughout the year. The subject C.V.C. had never had extended experience in any form of physical exercise. Both D.B.D. and A.V.B. have led sedentary lives but have been accustomed at times to periods of hard physical work. The former was a runner while in college. The study made in the case of DeMar covered a period of two weeks, the experiments being done before breakfast. The data in the case of C.V.C. were collected in a period of about six weeks, those on D.B.D. and A.V.B. in six months, the experiments generally being done 1-3 hours after breakfast. METHODS.The work experiments were performed on a stationary bicycle equipped with a Prony brake. The periods of work lasted for 20 minutes or longer.
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