from materials obtained directly from the living matter. They are of interest as showing possibilities of increases in enzyme activities, at present uncontrolled, which have been assumed, perhaps tacitly, to occur only during life processes. Decreases in enzyme actions are too common to consider in this connection, but such increases as are described compel attention. The selective increases in the lipase and protease actions indicate that the characters of the enzymes are changing and may perhaps parallel or correspond to changes in substances in the growth of living organisms. In general, the bearing of these relations upon the mechanism of the chemical transformations which occur in life processes is of interest.4 Summary Spontaneous increases in the lipase and protease actions of a number of tissue and tumor extracts are described. These increases were selective in character, taking place with certain substrates and not with others under the same conditions. The possible significance of such changes in action in connection with phenomena occurring in life processes is indicated.New York, N. Y.
On cooling, needle crystals separated which, after recrystallization from alcohol, gave 0.5 g. of light cream-colored needles which melted at 223°. The analytical data were satisfactory for the monofurfuryl ether of the diol.
The salt was dehydrated completely at 78°over phosphorus pentoxide. A sample of the salt weighing 25.270 ing. dried at room temperature over phosphorus pentoxide when completely dehydrated at 78°lost 0.378 mg. weight, or 1.50%. This dehydrated salt was analyzed for nitrogen.
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