The digital imaging method was faster and easier to use and the patients preferred it, as it was a noncontact method. In addition it also provides a photographic record for comparison.
BackgroundThe route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes.Case PresentationWe present a case report of testicular seminoma in a 56 year old man with previously unreported histological findings. In this case seminoma tumour cells did not appear to have spread by the expected lymphatic route. There was no involvement of retro-peritoneal para-aortic lymph nodes. The tumour appeared to have spread directly along the vas deferans in the sub epithelial plane to the mesenteric lymph nodes.ConclusionThis type of seminoma tumour spread has not previously been described and it is not a recognised route for metastasis by seminoma tumour. In this case the macroscopic clinical appearance was of a stage I tumour with normal tumour markers. However, the pathological stage of the tumour was surprisingly increased to stage III on the basis of histology and CT radiological findings. We present the unusual histological findings. In view of this unusual histological finding we reinforce the need for accurate staging and for resection of the spermatic cord close to the deep inguinal ring. Accurate staging is crucial in planning the treatment and follow up of seminoma and determines the prognosis.
We present an unusual case of a retained resectoscope beak detected 10 months following transurethral resection of a bladder tumour. We describe this rare complication after transurethral surgery and present a safe method for removing a resectoscope beak from the urethra. This case prompted several improvements in our local surgical checklists to prevent such an event from recurring. It is important to check the integrity of surgical equipment in addition to counting equipment in and out during theatre; without checking, as exemplified by the resectoscope in this case, we risk missing the point.
Despite the unequivocal contribution of targeted MRI fusion biopsy, it is known that ultrasoundguided biopsy with systematic sampling still is the main tool for prostate cancer (PC) diagnosis in developing countries. However, the number of sampled fragments remains a matter of controversy. Our objective was to compare the cancer detection rate (CDR) and the complications of 12 versus 20-core ultrasound guided transrectal prostate biopsy.METHODS: A prospective controlled study was conducted enrolling 758 consecutive patients who underwent biopsy with 1:1 randomization ratio for 12-core versus 20-core biopsy under periprostatic block local anesthesia. 76 patients were on active surveillance and 284 had at least one previous biopsy. The overall and the significant (Gleason 7) CDR were compared between the 2 techniques. We also evaluated the CDR according to PSA, free PSA, PSA density, prostate volume, previous biopsy and suspicious digital rectal examination. We assessed the occurrence of complications and the pain immediately after the procedure using the visual analogue pain intensity scale.RESULTS: The CDR was 47.7% and 37.7% in 20-core and 12core groups, respectively (OR 1.510; 95% CI: 1.130 to 2.018, p¼0.0052). An overall 18.5% significant increase in Gleason score 7 detection rate was found in the 20-core group (83.7 vs. 65.2% p¼0.0463). The CDR was also in favor of the 20-core when the active surveillance patients were excluded 45.6% and 32.9% (OR 1.712; CI 95% 1.215 to 2.412 p¼0.002). Considering only the surveillance patients the 20-core protocol also showed higher CDR 66.7 vs. 52.5% (p¼0,209). The CDR between the two techniques were similar according to PSA levels (p¼0.874), prostate volume p¼0.619), previous biopsy (p¼0.5973), age (p¼0.070), suspicious DRE (p¼0.146), free-tototal (p¼0.542) and PSA density (p¼0.585).The occurrence of any complication and acute prostatitis were similar between the 20-and 12core groups: 10.7 vs. 10.4% (p¼0.899) and 6.5 vs. 4.2% (p¼0.2166), respectively. The mean visual analogue pain intensity scale were also similar in 20-core when compared to 12-core group 2.35 vs. 2.19 (p¼0.7977).CONCLUSIONS: Our randomized trial revealed that the overall cancer positivity and the diagnosis of aggressive tumors were significantly higher in the 20-core prostate biopsy when compared to the 12core protocol. The complication rates and the pain experienced by the patients were similar in both groups.ClinicalTrials.gov NCT02825225
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