Magnetic particle imaging (MPI) is a promising medical imaging techniqueproducing quantitative images of the distribution of tracer materials (superparamagnetic nanoparticles) without interference from the anatomical background of the imaging objects (either phantoms or lab animals). Theoretically, the MPI platform can image with relatively high temporal and spatial resolution and sensitivity. In practice, the quality of the MPI images hinges on both the applied magnetic field and the properties of the tracer nanoparticles. Langevin theory can model the performance of superparamagnetic nanoparticles and predict the crucial influence of nanoparticle core size on the MPI signal. In addition, the core size distribution, anisotropy of the magnetic core and surface modification of the superparamagnetic nanoparticles also determine the spatial resolution and sensitivity of the MPI images. As a result, through rational design of superparamagnetic nanoparticles, the performance of MPI could be effectively optimized. In this review, the performance of superparamagnetic nanoparticles in MPI is investigated. Rational synthesis and modification of superparamagnetic nanoparticles are discussed and summarized. The potential medical application areas for MPI, including cardiovascular system, oncology, stem cell tracking and immune related imaging are also analyzed and forecasted.
The effects of vacuum annealing on the structural and transport properties of the La0.67Ca0.33MnO3−δ films grown on SrTiO3 (LCMO/STO) and NdGaO3 (LCMO/NGO) substrates have been studied. A lattice expansion due to oxygen release during the annealing is observed. Under the same condition, the change of the out-of-plane lattice parameter in LCMO/STO is two to three times larger than that in LCMO/NGO, indicating a strong tendency for the oxygen in the former to escape. Correspondingly, the metal-to-semiconductor transition shifts to lower temperatures, linearly with lattice constant until a critical value, Δd=0.03 Å for LCMO/STO and Δd=0.05 Å for LCMO/NGO, after which a sudden drop of the transition temperature to zero occurs. The different lattice strains in both films are presumably responsible for the different critical oxygen contents for the occurrence of the resistive transition.
Instead of using conventional electron lithography, a two-dimensional photonic crystal consisting of a hexagonal array of triangular air-holes was created on the surface of a GaN LED substrate using microsphere lithography. The microspheres self-assemble into a single-layered hexagonal-close-packed array acting as an etch mask. A significant enhancement in photoluminescence intensity was recorded from the PhC LED structure. A twofold increase in electroluminescence was observed from the PhC LED compared to an as-grown LED with identical geometry. Besides geometrical factors due to surface roughening, the dispersive nature of PhCs and diffractive properties of the PhC as a grating contribute to the enhancement of light extraction from the LED.
The problem of offline handwritten Chinese character recognition has been extensively studied by many researchers and very high recognition rates have been reported. In this paper, we propose to further boost the recognition rate by incorporating a distortion model that artificially generates a huge number of virtual training samples from existing ones. We achieve a record high recognition rate of 99.46% on the ETL-9B database. Traditionally, when the dimension of the feature vector is high and the number of training samples is not sufficient, the remedies are to (i) regularize the class covariance matrices in the discriminant functions, (ii) employ Fisher's dimension reduction technique to reduce the feature dimension, and (iii) generate a huge number of virtual training samples from existing ones. The second contribution of this paper is the investigation of the relative effectiveness of these three methods for boosting the recognition rate.
The topics of fingerprint classification, indexing, and retrieval have been studied extensively in the past decades. One problem faced by researchers is that in all publicly available fingerprint databases, only a few fingerprint samples from each individual are available for training and testing, making it inappropriate to use sophisticated statistical methods for recognition. Hence most of the previous works resorted to simple-nearest neighbor (-NN) classification. However, the-NN classifier has the drawbacks of being comparatively slow and less accurate. In this paper, we tackle this problem by first artificially expanding the set of training samples using our previously proposed spatial modeling technique. With the expanded training set, we are then able to employ a more sophisticated classifier such as the Bayes classifier for recognition. We apply the proposed method to the problem of one-to-fingerprint identification and retrieval. The accuracy and speed are evaluated using the benchmarking FVC 2000, FVC 2002, and NIST-4 databases, and satisfactory retrieval performance is achieved.
Pentacene organic thin-film transistors (OTFTs) using La x Nb (1Àx) O y as gate dielectric with different La contents (x ¼ 0.347, 0.648) have been fabricated and compared with those using Nb oxide or La oxide. The OTFT with La 0.648 Nb 0.352 O y as gate dielectric can achieve a high carrier mobility of 1.14 cm 2 V À1 s À1 (about 1000 times and 2 times those of the devices using Nb oxide and La oxide, respectively), and has negligible hysteresis of À0.130 V, small sub-threshold swing of 0.280 V/ dec, and low threshold voltage of À1.35 V. AFM and XPS reveal that La can suppress the formation of oxygen vacancies in Nb oxide while Nb can alleviate the hygroscopicity of La oxide, which results in a more passivated and smoother dielectric surface, leading to larger pentacene grains grown and thus higher carrier mobility. The OTFT with Nb oxide has an anticlockwise hysteresis but the device with La oxide shows an opposite direction. This can be explained in terms of donorlike traps due to oxygen vacancies and acceptor-like traps originated from hydroxyl ions formed after La 2 O 3 absorbing water moisture. V
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