Background and aimsStudies examining the next‐day cognitive effects of heavy alcohol consumption have produced mixed findings, which may reflect inconsistencies in definitions of ‘hangover’. Recent consensus has defined hangover as ‘mental and physical symptoms, experienced the day after a single episode of heavy drinking, starting when blood alcohol concentration (BAC) approaches zero’. In light of this, we aimed to review the literature systematically to evaluate and estimate mean effect sizes of the next‐day effects of heavy alcohol consumption on cognition.MethodsEmbase, PubMed and PsycNET databases were searched between December 2016 and May 2018 using terms based on ‘alcohol’ and ‘hangover’. Studies of experimental designs which reported the next‐day cognitive effects of heavy alcohol consumption in a ‘hangover’ group with BAC < 0.02% were reviewed. A total of 805 articles were identified. Thirty‐nine full‐text articles were screened by two independent reviewers and 19 included in the systematic review; 11 articles provided sufficient data to be included in the meta‐analysis; 1163 participants across 19 studies conducted since 1970 were included in the analysis. Data for study design, hangover severity, BAC at testing and cognitive performance were extracted and effect estimates calculated.ResultsThe systematic review suggested that sustained attention and driving abilities were impaired during hangover. Mixed results were observed for: psychomotor skills, short‐ (STM) and long‐term memory (LTM) and divided attention. The meta‐analysis revealed evidence of impairments in STM [g = 0.64, 95% confidence interval (CI) = 0.15–1.13], LTM (Hedges’ g = 0.59, 95% CI = 0.01–1.17) sustained attention (g = 0.47, 95% CI = 0.07–0.87) and psychomotor speed (Hedges’ g = 0.66, 95% CI = 0.31–1.00) during alcohol hangover.ConclusionThe research literature suggests that alcohol hangovers may involve impaired cognitive functions and performance of everyday tasks such as driving.
We report the fabrication of hybrid organic/inorganic semiconductor light-emitting devices that operate across the entire visible spectrum. The devices are based on a series of blue-, green-, and red-light-emitting polyfluorene materials that convert the emission from an array of micron-sized ultraviolet InGaN light-emitting diodes. We also demonstrate white-light-emitting versions of these hybrid devices by employing single films of carefully adjusted polyfluorene blends in which cascade energy transfer occurs between the constituent materials. The spectral and operating characteristics of the devices are described in detail. Such organic emission layer/inorganic light-emitting diode (LED) array based devices may provide a promising route to the fabrication of low-cost full-color microdisplays and other instrumentation devices.
We present the highlights of a research programme on hybrid inorganic-organic light emitters. These devices combine recent developments in III-V nitride technology (including UV emitting micro-arrays and specifically tailored quantum wells) with conjugated polymers to access the entire visible spectrum. Two types of devices are studied, those based on down conversion of the quantum well emission by radiative transfer and those based on non-radiative resonant energy transfer. The spectral and operating characteristics of the devices are described in detail. Selectable colour micro-arrays and bar emitters are demonstrated. The nature of the non-radiative energy transfer process has also been studied and we find transfer efficiencies of up to 43% at 15 K, with a 1/R 2 dependence on the distance between quantum well and polymer layer, suggesting a plane-plane interaction. The relative importance of the non-radiative resonant energy transfer process increases with temperature to be up to 20 times more efficient, at 300 K, than the radiative transfer process.
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