The relative bioavailability (RBV) of a dipeptide DL-methionyl-DL-methionine (DL-Met-Met) was compared with DL-methionine (DL-Met) in growing pigs (experiment 1; N-balance study) and in weaned pigs (experiment 2; performance study). In experiment 1, 42 barrows with an initial body weight (BW) of 21.0 ± 1.37 kg were assigned to 7 dietary treatments with 6 replicate/pigs per treatment in a nitrogen (N) balance study to evaluate the RBV of DL-Met-Met to DL-Met. A basal diet (BD) was formulated to be adequate for all amino acids with the exception of Met + Cys which was 68% of the requirement [4.7 g/kg standardized ileal digestible (SID) Met + Cys; 11.5 g/kg SID Lys] for 20-25 kg pigs. Three graded levels of DL-Met (0.3, 0.6 and 0.9 g/kg) and DL-Met-Met (0.306, 0.612 and 0.919 g/kg) were supplemented to the BD to create diets 2-7. In experiment 2, a total of 189 weaned pigs (initial BW of 10.2 ± 0.98 kg) were assigned to 7 dietary treatments with 9 replicates/pens of 3 pigs per treatment. The dietary treatments consisted of a Met-deficient BD (5.3 g/kg SID Met + Cys; 13.0 g/kg SID Lys) and the same 3 graded levels of DL-Met and DL-Met-Met as in Exp. 1. In experiment 1, supplementation with DL-Met or DL-Met-Met linearly decreased (P ≤ 0.01; linear) urinary N excretion and increased (P ≤ 0.02; linear) N retained (g/day), N retention (% of intake and % of absorbed). However, there was no effect of Met sources on all N balance parameters. Based on the slope-ratio regression the RBV for DL-Met-Met compared to DL-Met was estimated 111% [95% confidence interval (CI): 63-158%] for N retained (g/d), 109% (95% CI: 57-160%) for N retention (% of intake) and 98% (95% CI: 43-154%) for N retention (% of absorbed) on an equi-molar basis. In experiment 2, the overall average daily gain (ADG) and gain:feed ratio (G:F) increased linearly (P < 0.01) by supplementation with DL-Met or DL-Met-Met. The average daily feed intake increased by supplementation with DL-Met (P = 0.02) and DL-Met-Met (P = 0.09). For ADG, the RBV for DL-Met-Met was estimated 104% (95% CI: 66-141%) on an equi-molar basis by the slope-ratio. Based on G:F, the RBV for DL-Met-Met was estimated 117% (95% CI: 61-174%) on an equi-molar basis. The results of both experiments indicate that the bioavailability DL-Met-Met is not different and at least equally bioavailable as DL-Met as a Met source for pigs.
This study aimed to investigate the effects of different net energy (NE) levels of diets with reduced crude protein (CP) that were supplemented with amino acids on feeding behavior, performance and carcass characteristics of heavy pigs (100-130 kg). Pigs were randomly allocated to experimental groups under a randomized complete block design with initial body weight as the blocking criterion. There were 5 treatments (NE levels: 2300, 2388, 2475, 2563 and 2650 Kcal NE/kg, as-fed basis) with 13 pigs per treatment, and the animal was the experimental unit. The diets were based on corn, soybean meal and wheat bran. CP levels were similar between diets and approximately 2% below the requirement (13.9%). Pigs were weighed at the beginning and end of the experiment. Electronic feeder systems automatically recorded the visits to the feeders, the timing of meals, and the amount of feed consumed per meal. Based on these recorded data, daily feed intake was calculated and feeding behavior was evaluated. At the end of the experiment, the pigs were slaughtered for carcass evaluation. Net energy levels did not affect the average daily feed intake (P > 0.05) but did influence the feeding behavior of the pigs. The pigs fed the 2388, 2475 and 2563 kcal NE/kg diets had fewer (P < 0.05) daily meals than those fed the 2300 and 2650 kcal NE/kg diets. Thus, these animals occupied the feeders for less time daily (P < 0.05) compared to those fed the 2300 and 2650 kcal NE/kg diets. The average daily NE intake increased linearly (P < 0.01) with increasing NE; however, average daily gain did not differ (P > 0.05) between treatments. There was a quadratic relationship (P < 0.01) between feed efficiency and increasing NE levels. The feed efficiency of pigs fed the 2563 kcal NE/kg diet did not differ (P > 0.05) from that of pigs in the 2388 and 2475 kcal NE/kg treatments, but was 9% higher (P < 0.05) than in the 2300 and 2650 kcal NE/kg treatments. Furthermore, loin depth and loin eye area did not change significantly (P > 0.05) when NE levels increased from 2300 to 2650 kcal NE/kg in the diets. However, a linear effect (P < 0.01) was observed for hot carcass yield and a trend toward a quadratic effect (P < 0.10) for hot carcass weight, backfat thickness and lean percentage. Among the studied levels, 2388, 2475 and 2563 kcal NE/kg produced the best results for reduced CP diets fed to heavy pigs because the pigs occupied the feeders for less time and showed higher feed efficiency.
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