One hundred four consecutive cases of primary intracerebral hemorrhage hospitalized at the time of stroke were followed until death or for 1 year. All were treated nonsurgically. The 30-day mortality rate was 30%. Good clinical outcome and complete resolution of the lesion on computed tomography were observed in 49 and 13% of patients, respectively. Age, state of consciousness, and size of the hemorrhage on computed tomography scan were reliable prognostic indicators. The long-term survival rate, 66%, was higher than that previously reported and should be considered in future trials evaluating medical and surgical treatment of intracerebral hemorrhage. Data from community studies based on clinical diagnoses may underestimate the true incidence of primary ICH, whereas hospital-based series fail to reflect the early deaths of patients who never reach the hospital.3 " 5The availability of computed tomography (CT) has improved diagnostic accuracy, modifying the figures on incidence and mortality rate for primary ICH. 67We report data on the relative incidence, early mortality, outcome, and CT findings in a consecutive hospital-based series of patients with primary ICH. Our main objective was to describe the clinical course, CT findings, and prognostic factors in all surviving nonsurgical patients over a 12-month follow-up. Subjects and MethodsThe University Hospital is a public facility serving a central area of Rome. The vast majority of patients with acute stroke from this section of the city are admitted to this hospital, and they are referred to our stroke unit for their acute management. For our analysis we recorded age, sex, and arterial hypertension in medical history (repeated values of > 160/95 mm Hg and/or use of antihypertensive drugs). Neurologic examinations on admission and at discharge, including the Glasgow Coma

The therapeutic efficacy of orally administered clonazepam has been evaluated in 32 epileptic patients, with substantial improvement in 22. The drug is active in all types of seizures, particularly in myoclonus, petit mal absences, and partial complex epilepsy; it seems the drug of choice in generalized infantile organic epilepsy, although the treatment of these patients is still unsatisfactory. In some patients, the drug seemed less effective after months of therapy. Drowsiness is the main side effect.

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