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MORRICONE, LELIO, ALEXIS ELIAS MALAVAZOS) by an Mmode, color-doppler videofluoroscope. VAT in the obese patients was assessed by computed tomography (at L4 level). Results: The obese patients had a significantly larger internal diastolic left ventricular (LV) diameter (p Ͻ 0.05), a thicker end-diastolic septum (p Ͻ 0.001) and posterior wall (p Ͻ 0.001), a greater indexed (g/m 2.7 ) LV mass (p Ͻ 0.001), a higher atrial diastolic filling wave velocity (p Ͻ 0.001), a lower ratio between early and atrial diastolic filling wave velocities (p Ͻ 0.01), and a prolonged isovolumic relaxation time (p Ͻ 0.05). End-diastolic septum and posterior wall thickness and the LV mass were significantly greater in patients with a VAT area Ͼ130 cm 2 than with Ͻ130 cm 2 . In the multivariate regression analysis, only VAT (p Ͻ 0.0001), waist-to-hip ratio (p Ͻ 0.001), and sex (p Ͻ 0.001) were associated with the most important echocardiographic alterations. Discussion: The morphological and functional echocardiographic alterations usually found in normotensive obese patients closely correlate with the amount of intra-abdominal fat deposition, even in the presence of diabetes or IGT.

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