Background: Most diseases of the breast present as a palpable mass. The majority of breast lesions are not malignant, and most benign lesions do not progress to cancer; however, the accuracy of diagnosis can be increased by a combination of preoperative tests like physical examination, mammography, fine-needle aspiration cytology (FNAC), and Trucut needle biopsy (TGNB) or core needle biopsy (CNB). FNAC has grown in popularity and became the first initial used procedure after history taking and clinical examination for diagnosis of solid and cystic breast lumps. This study was designated to investigate the accuracy of FNAC in comparison to TCNB for diagnosis of breast masses, Design: Retrospective Study.Methods: In this study, 62 patients having breast lumps were studied during the period from January 2014 to January 2017 in terms of FNAC and Trucut Biopsy and were compared with tissue diagnosis. Variables like age, marital status, duration, size, menstrual status and site were analyzed using statistical analysis.Results: Out of 62 patients with breast lump, 32 were diagnosed with Benign Breast lesions, and 30 with malignant lesions. Sensitivity of FNAC and TRUCUT biopsy were 84.34% and 97.1% respectively. TRUCUT was more accurate when compared to FNAC.Conclusions: Both FNAC and Core Needle Biopsy are complimentary to each other and are useful in diagnosis of breast lesions.
Background: Chronic non-healing wounds are one of the major burden to the patients in the present era and covers about 1% of adult population and 3.6% of the population greater than 65 years. Chronic leg wounds are the common cause of morbidity and its prevalence in the community range from 1.9 to 13.1%. Indian studies show the prevalence of chronic wounds of around 4.5/1000 population. Recent studies have shown that application of a sub atmospheric pressure in a controlled manner to the wound site helps significantly in wound healing. Aim of the present study is to assess the efficacy of topical negative pressure moist wound dressings in wound healing process in chronic wounds and to prove that negative pressure dressings can be used as a much better treatment option than conventional saline dressings in the management of chronic wounds.Methods: After 10 days, in study group the mean rate of granulation tissue formation, mean graft, mean hospital stay was 81.7%,80.6%, 34.7 days respectively and the same in control group it is 41.9%. ,60.45%, 58.60 days respectively.Results: To conclude, topical negative pressure dressing’s help in faster healing of chronic wounds and better graft take up and reduces hospital stay of these patients.Conclusions: The database of our retrospective study regarding age and sex incidence, clinicopathological features and therapeutic outcome was comparable to other studies in various literatures.
A 45 year man presented to Surgery opd with chief complaints of rectal bleeding and constipation for 1 month. There was no history of pain and mass per rectum. There was a history of histopathological and immunohistochemistry proven retroperitoneal leiomyosarcoma (Figure 1) for which he was operated in tertiary center 8 months back. Colostomy was done and was closed after 3 months. He received 2 cycles of gemcitabine and docetaxel based chemotherapy.His physical exam was unremarkable other than a digital rectal exam which revealed a firm mass in the posterior rectal wall. Biopsy from the mass was taken. Histopathology revealed differential diagnosis for leiomyosarcoma and gastrointestinal stromal tumour (GIST). (Figure 2) IJBR (2013) 04 (05) www.ssjournals.com AbstractLeiomyosarcoma is a rare malignancy of smooth muscle. Leiomyosarcoma may arise from the retroperitoneum and present with nonspecific signs and symptoms. The most common presentation is abdominal pain. In the past gastrointestinal stromal tumour (GIST) were misdiagnosed as leiomyosarcoma. GISTs however have been shown to lack features of smooth muscle tumors on histopathology. They are often CD34 and CD 117 immunoreactive in contrast to leiomyosarcoma. We present a rare case of retroperitoneal leiomyosarcoma with gastrointestinal stromal tumour of rectum in the same patient.
Apocrine malignancies are rare to occur. Axilla and the anogenital skin are the most common sites of primary tumour. Apocrine malignancy carries high risk of lymphatic and vascular spreading to lung, liver and bone. A 40 years old painter, presents with diffuse swelling and pain in the left lower limb up to left inguinal region since 5 to 6 months. With generalised lymphadenopathy. On evaluation, revealed adenocarcinoma of apocrine, skin adnexa in the extremities of the limb with extensive distant metastasis. Apart from Dermatologists other board specialty consultant should be aware of the possibility of apocrine adenocarcinoma while differentiating cutaneous tumor located in the extremities. Apocrine malignancy should be treated aggressively with wide local excision or amputation the involved part for improving the life expectancy. Since prevalence of apocrine malignancy are rare, and it is associated with increased mortality, it provoke us the field of research for discovering other modalities of treatment.
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