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This paper suggests a beat detection method for ballistocardiogram (BCG) from an unconstrained cardiac signal monitoring devices. A fiducial peak point of BCG is an I-J-K complex which corresponds with ventricle contraction and Electrocardiogram (ECG) QRS complex. The goal of the method is extraction of J peak without ECG synchronization. The detection method is based on a "template matching" rule evaluated using a correlation function in a local moving-window procedure. The total beat detection algorithm operates in two stages, template definition stage and beat detection stage with defined template in previous stage. In the first stage, the BCG template is constructed by the expert with an empirical analysis of BCG signal and measurement device. In the second stage, the correlation function calculates an accuracy of template with BCG signal using a local moving-window. The data analysis has been performed on the subjects tested at Seoul National University Hospital Sleep Medicine Center and presents 95.16% of sensitivity and 94.76% of positive predictivity value for the J peak detection.
This paper introduces a new method, bed actigraphy (BACT) for user-friendly sleep-wake monitoring. BACT provides a non-intrusive acquisition of activity data, and in particular does not require that sensors be attached to the subject's body. The system consists of four load-sensing cells supporting the bed, an A/D converter, and a microcontroller with appropriate software. The performance of BACT was compared to that of standard polysomnography (PSG) recordings and wrist-worn actigraphy (ACT). Ten normal volunteers underwent overnight PSG recordings and were examined simultaneously with BACT and ACT. An automatic scoring algorithm scored each 30-s epoch of the BACT recordings for either 'Wake' or 'Sleep.' A sleep specialist manually scored the PSG recordings, and the results were divided into 'Wake' and 'Sleep' categories. The three methods showed a significant correlation when compared with in the contingency test. The mean epoch-by-epoch agreements between the BACT and PSG, ACT and PSG, and BACT and ACT recordings were 95.2, 92.9, and 94.3%, respectively. The mean absolute differences in sleep percentage (SP) between them were 1.8 +/- 0.82, 3.4 +/- 1.45, and 1.9 +/- 1.16 %, respectively. BACT differentiation of the 'Wake' and 'Sleep' stages proved to be sufficiently robust, and its results were comparable to PSG analysis. This finding supports the experimental and clinical value of bed-activity monitoring during sleep.
We mapped spatially varying intramolecular electronic structures on a pentacene-gold interface using scanning tunneling spectroscopy. Along with ab initio calculations based on density functional theory, we found that the directional nature of the d orbitals of Au atoms plays an important role in the interaction at the pentacene-gold contact. The gold-induced interface states are broadened and shifted by various pentacene-gold distances determined by the various registries of a pentacene molecule on a gold substrate.
We have measured Ce 4f spectral weights of extremely alpha-like Ce transition metal intermetallic compounds CeRhx (x=2,3) and CeNix (x=2,5) by using the bulk-sensitive resonant photoemission technique at the Ce M5(3d(5/2)-->4f) edge. High energy resolution and longer escape depth of photoemitted electron at this photon energy enabled us to distinguish the sharp Kondo resonance tails at the Fermi level, which can be well described by the Gunnarsson-Schönhammer calculation based on the Anderson impurity Hamiltonian. On the other hand, the itinerant 4f band description shows big discrepancies, which implies that Ce 4f electrons retain localized characters even in extremely alpha-like compounds.
Polysomnography is the standard method to score the sleep stages or to determine the quality of sleep. During all night examination, subjects must attach complicate and numerous electrodes on their body to acquire the biosignals. They can influence participants' sleep stage transition or sleep pattern, and the method seems intricate. In many researches, it is reported that autonomic nervous system (ANS) is varying with sleep stage transition and heart rate variability (HRV) is one of the indices which reflects the changes of autonomic nervous system. In this point of view, we can estimate the sleep quality by observing the HRV variation. In this study, to analyze the heart rate variability, we introduce a new system that can detect the heart beats of subjects during sleep by using bed installed load-cell sensors. The pressure to the sensor changes with the pulsation of the heart and we consider it as ballistocardiogram, the physical heart beat signal. To validate our system, we adopted this system for the 4 subjects with the polysomnography. The results show the LF/HF ratio of the heart rate, one of the reflection parameters of ANS, acquired from the system for each sleep stage. To validate the results, the HRV from electrocardiogram using Ag-AgCl electrodes will be compared.
Polysomnagraphy, the method evaluating the sleep quality, is the reliable and standard method. However, to perform it, subject has to attach many sensors to their body. It seems intrusive, tangled and interrupting the subjects sleep. For the sake of monitoring the daily sleep pattern, simple method measuring the biosignal nonintrusively is needed. At that point, respiration is a beneficial signal, because it can be easily acquired by check the change of the thorax or abdomen. Respiration is one of the representatives of the reflection of the autonomic nervous system. According to the transition of the sleep stages, autonomic nervous system also changes and it can be shown by respiration.In this study, REM and non-REM sleep is classified by only using respiration for the 3 subjects. To enhance the performance, activity signal acquired by load-cell installed bed is added to divide the wake and REM sleep. At the results, hypnograms with polysomnagraphic data is compared with them. It can be seen that high correlation between the REM sleep and increasing pattern of the respiration rates.
Ran-Ju Jung et al. Reply:In the preceding Comment [1] on our recent Letter [2], Kucherenko et al. claimed that our conclusions on the localized character of f states in strongly -like Ce compounds are not convincing since cross-section and final-state effects were not properly taken into account. They mentioned that itinerant 4f contributions should be subtracted from the calculated density of f states (f-DOS) for a comparison with resonant photoemission (RPE) spectra because these itinerant states are not enhanced by the RPE process. We agree that such difference of resonance enhancement exists depending on the degree of localization, but we believe this effect is not big enough to change our main conclusion. Looking at Fig. 1 in the Comment [1], we can see that the experimental results are still not well reproduced by this subtraction procedure (hatched curves). The discrepancies between theory and experiment become weaker, but are still strong enough to imply the ''localized'' picture is a better starting point. And the fact that the subtractions affect only weakly the features close to the Fermi energy where the ''localized'' picture and ''itinerant'' picture make main discrepancies implies that our approach [2] describes the main aspects of this problem. As for our remark that CeRh 2 is closer to itinerancy than CeRh 3 , it is only in the sense that DOS fitting with self-energy corrections gives better agreement in CeRh 2 . We do not dispute the importance of the hybridization between Ce 4f state and the d states of transition-metal elements in these extremely -like compounds, as stated clearly in the Introduction (third paragraph) of our Letter [2]. And we also found that the hybridization of 4f and valence band states is stronger for CeRh 3 than for CeRh 2 from our Anderson impurity model fitting, in agreement with the band-calculation results of the Comment. Since there is no unique measure of ''itinerancy,'' we suppose there is no real physical significance to determine which is closer to the itinerancy.Kucherenko et al. also proposed that further aspects like final-state effects due to the specific geometry of the experiment should be considered for a proper comparison of the calculated f-DOS with RPE data. For this point, we have discussed the photon energy dependence of 3d ! 4f RPE spectra in another publication [3]. And considering that our RPE data were taken from scraped polycrystalline samples [2], we believe the specific geometry of the ex-3
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