Background: Aloe vera (AV) contains a variety of characteristic antibiotic and anti-inflammatory components that have potential advantages for periodontal disease therapy. Diagnostic and prognostic markers of periodontal disease through the activity of alkaline phosphatase (ALP) in gingival crevicular fluid. This study was conducted to evaluate the effect of giving AV gel on alkaline phosphatase levels in rats with bacteria-induced periodontitis Method: Thirty-six male Sprague dawley were healthy and active, weighing 170-200 grams, aged 2 months were distinguished into two groups: the control group of periodontitis given therapy Gel Metronidazole plus 25% and AV gel 99.03% as a treatment group. Aloe vera gel is administered topically in gingival sulcus at a dose of 300 mg/kg of rat weight. Samples were taken from gingival sulcus liquid on days 1, 2 and 3 using periopaper paper. Alkaline phosphatase levels are measured using a UV/Vis Spectrophotometer with a wavelength of 405 nm. Variant analysis is used to compare ALP levels in different groups Result: There was significant difference in alkaline phosphatase levels between the control group and the treatment group (p>0.05). In Sprague dawley rats with periodontitis, there was a significant decrease in ALP levels on days 1, 2 and 3 given Metronidazole gel plus 25% therapy and AV gel 99.03%. But the treatment group showed lower ALP levels than the control group Conclusion: This study revealed that the use of AV gel locally has an effect and can be as an adjunct therapy for periodontitis PENDAHULUANPeriodontitis merupakan salah satu masalah utama kesehatan mulut yang mempengaruhi kesehatan tubuh secara keseluruhan dengan prevalensi kasus 70% dari jumlah populasi global. 1 Penyakit inflamasi ini disebabkan oleh biofilm bakteri yang merusak jaringan penyangga gigi (ligamen periodontal, gingiva dan tulang alveolar) atau sering disebut jaringan periodonsium. 2 Aktivitas inflamasi yang terjadi di jaringan periodonsium dapat ditentukan melalui kadar alkaline phosphatase (ALP) dalam cairan sulkus gingiva (GCF). 3 Alkaline phosphatase adalah salah satu marker diagnostik pertama yang diidentifikasi dalam GCF dengan kadar lebih tinggi daripada di serum. 4 Alkaline Phosphatase tersimpan dalam granul spesifik dan vesikula sekretori neutrofil yang akan sekresikan dan bermigrasi ke daerah inflamasi. Analisis ALP pada cairan sulkus gingiva merupakan pendekatan yang paling praktis untuk analisis biokimia dari respon host pada penyakit periodontal. 5 Kadar ALP dapat diukur pada 0 jam sampai 14 hari dengan puncak kadar ALP pada hari ke 14 sebesar 56.75±11.50 IU/L. 4 Kenaikan kadar Alkaline Phosphatase secara signifikan pada cairan
The asessment of cranio-facial structures forms a part of orthodontic diagnosis and treatment. One of the most frequently used cephalometric analysis is the Down’s analysis. It consists of 10 parameters of which 5 are skeletal and 5 are dental. Down has based his findings on 20 Caucasians, which have physical characteristic differences with Papuans. Indigenous Papuans are people of Melanesian descent consisting of indigenous tribes in Papua province and/or people who are accepted and recognized as Papuans by indigenous Papuans.The use of cephalometric values in different racial types, may result in the incorrect orthodontic diagnosis and treatment plan. According to those, the objectives of this study are to determine reference values for Down’s cephalometric analysis in papuans, to evaluate the differences exists between Papuan adult male and female, and also to compare the mean difference between persent study and established value of Down’s norms. A study was conducted on 16 lateral cephalograms of Papuans that have been selected based on inclusion criteria. The Down’s method was used for the cephalometric analysis. The data obtained was processed statistically to determine the mean, standart deviation, and minimum-maximum value, and presented in the form of frequency, table, or diagram. The result showed that the normal cephalometric values of papuans different from the normal values used in the Down’s analysis. The values obtained in this research is expected to be a reference in conducting Down’s cepahlometric analysis in Papuans for orthodontic treatment purposes.
Background:The use of fixed orthodontics is not a new thing for the community. The rapidly increasing information has changed people's understanding of the use of fixed orthodontic appliances where the initial function of fixed is for health, but along with changes in one's knowledge, the use of fixed orthodontics has turned into a style or trend that aims to make the appearance more attractive. Most of the youth are currently doing fixed orthodontic treatment only for a lifestyle, trend or style without knowing the complaints and goals of fixed orthodontic treatment. In addition, most teenagers do not know the orthodontic treatment that should be carried out by orthodontic specialist dentists. This study aims to specifythe description of adolescents aged 14-18 years in SMA Negeri 1 Belitang, South Sumatra province regarding the side effects of using orthodontic appliances. Method: This is a descriptive observational using a cross sectional study. The sampling technique used is total sampling with a total of 50 respondents. Result:The results of the study revealed that adolescents' knowledge of the side effects of using fixed orthodontic appliances was in the good category of 13 subjects (26%), sufficient category 29 subjects (58%), and less category 8 subjects (16%). Conclusion:The conclusion of this study is that the knowledge possessed by adolescents aged 14-18 years at SMA Negeri 1 Belitang, South Sumatra Province regarding the side effects of using orthodontic appliances is quite good in as many as 29 subjects(58%).
Background: Riskesdas data in 2018 showed a 57.6% dental and oral problems prevalence. One of the abnormalities of the teeth and mouth is malocclusion. Malocclusion can be fixed by performing orthodontic treatments performed by orthodontist dentists. However, because orthodontic care requires a considerable cost, those with low economy and education look for alternatives by performing orthodontic treatments to dental artisans. Objectives: This study evaluates the patient's quality of life (QoL) with fixed orthodontic treatment by dental artisans (denturists) using the OHIP-14 questionnaire. Methods: The research method used is descriptive observational, where samples are taken by random sampling of the 67 patients who used fixed orthodontic treatment by denturists. This research applied a cross-sectional study conducted by collecting data only using the OHIP-14 questionnaire at a time without further investigation. The data analysis applied was the Univariate Statistical test. Results: The results of the total score obtained from the dimensions of functional limitations are 238 (moderate category), physical pain is 220 (moderate category), psychological discomfort is 205 (moderate category), physical disability is 232 (moderate category), psychological disability is 225 (moderate category), social disabilities is 230 (moderate category), the barriers is 246 (bad category). Conclusion: Several factors caused denturists' impaired QoL of patients in fixed orthodontic treatment, with six as moderate categories and one as poor.
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