to the development of comorbidities, such as childhood obesity -a chronic-degenerative and multifactorial disease that is considered as one of the biggest public health problems in the world. Objective: Investigate, interpret and review the findings on breastfeeding and its connections with childhood obesity. Methodology: The Medical Literature Analysis and Retrieval System Online (MEDLINE/PubMed) databases were used, under the descriptors "Breastfeeding" and "Childhood obesity", with the selection of review articles and original articles, following criteria of eligibility. 833 texts were found, with an initial selection of 139, of which 22 eligible articles remained. Results: The articles, written in English, also included publications by authors and journals of different nationalities. Most articles covered the years 2016 (four) and 2018 (four), and most of them were published in the last five years. Final considerations: It is evident that breastfeeding brings benefits both in the short term, since it provides adequate nutritional support necessary for the initial development of the child, as well as in the long term, being an important protective factor against childhood obesity.
O SARS-CoV-2 pode ter provocado um aumento dos casos da Síndrome Inflamatória Multissistêmica Pediátrica (SIM-P), causando choque e falência de órgãos. O objetivo do artigo foi elucidar o que avaliar para diagnosticar a SIM-P associada í COVID-19. Método: Revisão bibliográfica na plataforma Evidence Aid e Pubmed com os descritores: pediatric multisystem inflammatory syndrome e COVID-19. Encontrou-se 89 artigos, selecionando 26 após triagem. Adicionou-se, manualmente, 2 boletins epidemiológicos e 1 postagem da Sociedade de Pediatria de São Paulo. Resultados: Os aspectos epidemiológicos, a presença de febre, rash cutâneo e alterações gastrointestinais e cardíacas, ajudam a caracterizar a síndrome. Nos exames laboratoriais são encontrados aumento de: proteína C-reativa, D-dímero, procalcitonina, ferritina sérica, fibrinogênio e marcadores cardíacos. Conclusão: A identificação das alterações é crucial para o diagnóstico diferencial e correto da SIM-P. Ademais, a padronização da coleta de dados e a identificação e descrição dos sinais e sintomas cooperaria para o diagnóstico.
Context: The Broca’s (BA) and Wernicke’s Area (WA) are fundamental for the language function. Surgical interventions in proximal areas can cause functional deficits. The left brain (LB) contains BA and WA in 92.5-97% of the right-handed individuals and 2/3 of the left-handed. The mapping of these functional areas is done with functional magnetic resonance (fMRI), which identifies which cerebral hemisphere is responsible for to the language function. In slow-growing tumor lesions, there might be plasticity in these areas, which allows tumor resection with functional recovery. In high-grade tumors, growth is fast and there is usually no significant plasticity. This article aims to demonstrate that even in high-grade tumors, brain plasticity in language areas can occur. Case report: T.R.P., male, 20 years old, right-handed, with type-2 neurofibromatosis. Evaluated due to the epileptic seizure with a lesion suggestive of high-grade glioma (IV-WHO) affecting the lower frontal gyrus in magnetic resonance imaging. Results: Undergoing surgical resection with awake craniotomy for functional language mapping. Functional studies have shown that the anatomical area corresponding to BA had no function and was surgically removed. T.R.P. evolved without functional deficits and fMRI showed complete resection of the Broca’s area and the anatomo-pathological exam confirmed that the tumor was a high-grade Glioma (IV-WHO). Conclusions: Even in the presence of a fast-growing lesion, the possibility of brain plasticity in the language areas should be considered. When plasticity is found, complete resection of the tumor is possible using invasive brain mapping, which has a direct impact on prognosis and survival.
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