No abstract

Lamotrigine is a new generation antiepileptic which blocks sodium channels and can cause significant toxicity in overdose. A case of a three-year-old child who suffered a seizure and required endotracheal intubation after accidental lamotrigine ingestion is presented. The lamotrigine concentration measured 23.2 mcg/mL which is the highest reported after accidental pediatric exposure. A review of the literature regarding pediatric lamotrigine poisoning is also included.

was systematically covered largely accounts for the fall now occurring in the number of cases of cervical cancer in Aberdeen. In the interests of economy, and in the light of our knowledge of the high-risk groups, should the taking of smears not become part of all routine antenatal care? The majority of cases would then be detected before the high-risk patient had finished childbearing. Twenty years later a fall in the incidence of the disease could be predicted, a fall which will never happen if only the well women offering themselves for screening and rescreening are covered.