Myxofibrosarcoma is recognized as a malignant neoplasm of fibroblastic origin
with increased prevalence in the elderly, presenting as nodules or tumors that
may extend to the dermis and skeletal muscle, preferably in the lower limbs.
Histologically it is characterized by a proliferation of spindle cells in a
myxoid stroma. Myxofibrosarcoma has a high potential for local recurrence and
metastasis, mainly when it presents a high or intermediate histological grade.
We report the case of an eighty-four year old patient with a difficult diagnosis
of a highly aggressive tumor.
This study showed that treatment of LUTD in children must be individualized, and requires constant monitoring of clinical, laboratory and imaging to minimize the risk of kidney damage.
The etiology of pityriasis lichenoides is unknown. One of the accepted theories
admits that PL is an inflammatory response to extrinsic antigens such as infectious
agents, drugs and vaccines. In recent medical literature, only the MMR vaccine
(Measles, Mumps and Rubella) was associated with the occurrence of this disease. We
present a case of a male, 12 year old healthy patient who, five days after Infl uenza
vaccination, developed erythematous papules on the trunk, abdomen and limbs, some
with adherent crusts and associated systemic symptoms. This case report is notable
for describing the first case of pityriasis lichenoides et varioliformis acuta
associated with the vaccine against Influenza.
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