A 48-year-old male with a history of familial hypercholesterolemia treated with evolocumab subcutaneous since 2017 developed recurrent episodes of acute uveitis. The most common diseases associated with uveitis were ruled out. Physical examination revealed an arcus senilis in both eyes. To the best of our knowledge, there have been no cases of uveitis reported with the use of evolocumab. We discuss a possible mechanism for the development of uveitis in this case. We conclude that acute anterior uveitis is a possible side effect related to the use of this medication.
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