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La codigestión anaerobia (CA) es una de las opciones viables para superar las desventajas de la mono-digestión. Esta investigación presenta los resultados del Potencial Bioquímico de Metano (PBM) donde se evaluó la CA de biorresiduos municipales (BM) de una localidad que realiza separación en la fuente y recolección selectiva con lodos de aguas residuales domésticas (LARD) provenientes de una planta de tratamiento de aguas residuales en diferentes proporciones de mezcla. Se evaluó la producción de metano mediante el modelo modificado de Gompertz y la hidrólisis a través del modelo cinético de primer orden, ya que esta es la etapa limitante en la CA de residuos sólidos. La proporción de mezcla LARD:BM donde se lograron las mayores producciones de metano (105.6 mLCH4·gSV-1), mejores constantes de hidrólisis (Kh) y fases de latencia cortas (menores a 3.3 días) fue 20:80.

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Organic amendments favor the development of sustainable agriculture by using less chemical fertilizers. In this way, the use of digestates from anaerobic digestion as soil conditioners in agriculture has been gaining interest due to their important N and P nutrient contents, among others. This study evaluated the potential use of digestates from anaerobic reactors treating food waste in single (D1) and two-stages (D2: hydrolytic/acidogenic and D3: acetogenic/methanogenic) configurations. Digestate characteristics and their potential application conditions (100, 50, 25, and 5%) were evaluated using Raphanus sativus as an indicator species. D3 reported the best performance in terms of: (i) better physicochemical, microbiological, and parasitological characteristics, being a class B material, without exceeding the established limits for heavy metals, fecal coliforms (FC <  1000 CFU 100 mL− 1), Salmonella spp. (0 CFU g− 1), and viable helminth eggs (0 HE g− 1); (ii) better stability indicators on D3, followed by D1 (volatile solids/total solids (VS/TS): 0.57 and 0.65, pH: 8.63 and 6.80, respectively), while D2 was the most unstable digestate (VS/TS > 0.87 and acidic pH); and (iii) greater potential for agricultural use, since a 5% dose produced a germination index > 120%, whose effect is associated with the presence of humic and fulvic acids and with N and P concentrations > 1%. In addition, the study reported that volatile fatty acids > 2500 mg L− 1 act as antimicrobial agents, reducing the required pathogen removal pretreatments.