The use of closure devices for an antegrade approach up to 10F is feasible and safe. No differences in low complication rates were observed between CFA and SFA.
ZusammenfassungDer laryngopharyngeale Reflux (LPR) ist durch ein Aufstoßen von gastralem bzw. gastroduodenalem Sekret wie auch von gasförmigem Inhalt in den oberen aerodigestiven Trakt charakterisiert, wodurch eine Schädigung der Schleimhäute u. a. im Larynx- und Pharynxbereich resultieren kann. Eine Reihe von Symptomen wie das klassische retrosternale Brennen und saure Aufstoßen oder weitere, teils sehr unspezifische Symptome wie Heiserkeit, chronischer Husten, zervikales Globusgefühl oder Hypersekretion von Mukus können daraus resultieren. Bei heterogener Studienlage und dem Fehlen eines Goldstandards ist, wie kürzlich zusammengefasst, die Diagnosestellung des LPR schwierig und umstritten. Die Therapieoptionen des LPR werden aufgrund der dünnen Datenlage ebenfalls kontrovers diskutiert und können neben medikamentösen auch konservative diätetische Maßnahmen umfassen. Das Ziel der nachfolgenden Übersichtsarbeit ist daher, die verfügbaren therapeutischen Optionen des LPR kritisch zu diskutieren und für den praktischen klinischen Alltag zusammenzufassen.
<b><i>Introduction:</i></b> Chronic rhinitis (CR) and rhinosinusitis are prevalent conditions affecting people all over the world. Their exact relationship is still not fully understood. We sought to find out, whether CR is a risk factor for chronic rhinosinusitis (CRS) and which main subgroup or other factors could be predisposing. <b><i>Methods:</i></b> Patients with diagnosed CR between 2005 and 2010 were selected from the electronic medical record and were contacted by phone call. They were interviewed and screened for possible CRS using internationally approved questionnaires, e.g. NOSE-D and SNOT-20-GAV. Those with elevated scores were invited for a clinical examination. <b><i>Results:</i></b> Of 113 patients available for statistical analysis (48/65 = f/m), mean age of 52 ± 15 years, 13 patients were diagnosed with CRS. Extrapolated for the total cohort of 334, calculated prevalence was 9.5%. No statistical significantly higher probability of developing CRS for either main subgroup of CR was found. Age of onset, prior surgery of the nose, and use of topical nasal treatments were associated with the development of CRS in multivariate analyses (OR = 0.1, 3.2, and 3.2, respectively). <b><i>Discussion/Conclusions:</i></b> Only a small number of rhinitis patients developed CRS, questioning the paradigm of CR being a clear risk factor for CRS.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.