This study presents a method for the fabrication of solvent‐resistant poly(dimethylsiloxane) (PDMS) microfluidic devices by coating the microfluidic channel with a hybrid inorganic/organic polymer (HR4). This modification dramatically increases the resistance of PDMS microfluidic channels to various solvents, because it leads to a significant reduction in the rate of solvent absorption and consequent swelling. The compatibility of modified PDMS with a wide range of solvents is investigated by evaluating the swelling ratio measured through weight changes in a standard block. The HR4‐modified PDMS microfluidic device can be applied to the formation of water‐in‐oil (W/O) and oil‐in‐water (O/W) emulsions. The generation of organic solvent droplets with high monodispersity in the microfluidic device without swelling problems is demonstrated. The advantage of this proposed method is that it can be used to rapidly fabricate microfluidic devices using the bulk properties of PDMS, while also increasing their resistance to various organic solvents. This high compatibility with a variety of solvents of HR4‐modified PDMS can expand the application of microfluidic systems to many research fields.
The direct synthesis of hydrogen peroxide (DSHP) from
H2 and O2 is conceptually the most ideal and
straightforward
reaction for producing H2O2 in industry. However,
precisely tailored catalysts are still in progress for large scale
production. Here, we report highly efficient and industrially relevant
catalysts for the direct synthesis of H2O2 from
H2 and O2 prepared by the immobilization of
Pd nanocatalysts onto a functionalized resin. The continuous production
of 8.9 wt % H2O2 and high productivity (180
g of H2O2 (g of Pd)−1 h–1) is achieved under intrinsically safe and less-corrosive
conditions without any loss of activity. We expect this approach is
a substantial improvement of nanocatalysts for direct synthesis of
hydrogen peroxide from hydrogen and oxygen and will greatly accelerate
the industrially relevant process of on site production of hydrogen
peroxide soon.
A facile route for cell patterning on functionalized surface with polyelectrolyte (PEL) and polyethylene glycol (PEG) microstructures is presented. Controlled cell adhesion is achieved by a micromolding in capillaries (MIMIC) on PEL coated surface, which produced two orthogonal regions including PEG region as physical and biological barriers to the nonspecific binding of cells and PEL surface for promoting cell adhesion. Our simple method but universal platform shows the first capable of versatile cell patterning from bacteria to animal cells. Although the adhesive proteins are necessary for the successful cell adhesion, our proposed method provide affordable surface for cell adhesion without adhesive proteins. In addition, the approach will be easily applied to various substrates such as glass, silicon, silicon oxide, and polymers.
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