This study examines the effectiveness of cigarette warning labels, with a specific focus on the impact of graphics, message framing (gain vs. loss), and temporal framing (present-oriented vs. future-oriented) among nonsmokers in the United States. A controlled experiment (N = 253) revealed that graphic warning labels were perceived as more effective, stronger in argument strength, and were generally liked more compared to text-only labels. In addition, loss-framed labels, compared to their gain-framed counterparts, were rated higher in perceived effectiveness, argument strength, and liking. No significant difference was observed between the present- and future-oriented frames on any of the dependent variables. Implications of the findings for antismoking communication efforts are discussed.

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Background As user modification can alter the addictiveness and toxicity of electronic nicotine delivery systems (ENDS), more research is needed to understand the types, motivations, risks, and information sources that lead to these product alterations. YouTube has been identified as a major platform where ENDS users obtain and share information about ENDS products and modifications. However, a comprehensive study of ENDS modification videos on YouTube is lacking. Objective This study aimed to analyze the content of YouTube videos depicting modifications of ENDS. Methods YouTube was searched in March 2019 to identify videos depicting ENDS modifications. Search terms were derived from interviews with ENDS users and current literature. We used 28 search phrases that combined the words vape and vaping with modification-related key terms (eg, custom build, modification, and dripping). The final sample included 168 videos. Results Videos were 1 to 108 min long (median 9.55). Presenters were largely male (117/168, 69.6%), white (94/168, 56.0%), and older than 25 years (94/168, 56.0%). Most videos gave how to instructions (148/168, 88.1%), but few offered warnings (30/168, 17.9%) or mentioned commercial alternatives to modifications they presented (16/168, 9.5%). The ENDS devices most often featured were drippers (63/168, 37.5%) and refillable tanks (37/168, 22.0%). The most often modified ENDS components were coils (82/168, 48.8%) and e-liquids (34/168, 20.2%), which included adding other substances, such as cannabis, to the e-liquids (6/168, 3.6%). Most videos portrayed ENDS modifications positively (106/168, 63.1% positive; 60/168, 35.7% neutral; and 2/168, 1.2% negative) and were either neutral or positive in their overall portrayal of ENDS devices (78/168, 46.4% positive; 89/168, 53.0% neutral; and 1/168, 0.6% negative). Conclusions This study identified several concerning trends in popular YouTube videos on ENDS modifications, including lack of warnings, the addition of marijuana derivatives to e-liquids, and the positive portrayal of ENDS devices and modifications. By identifying the types of modifications (coil and e-liquid being the most prevalent), this study sets an agenda for research on the effects of modifications.

Comparative risk communication might encourage smokers to switch to lower-harm tobacco products. Comparative risk messages with more negative antismoking elements in the design might be particularly effective, because they led to higher self-efficacy to quit smoking. Regulatory agencies may consider using comparative risk messages with more negative antismoking elements to educate the public about lower risk of e-cigarettes.

Abstract. MicroRNAs (miRs) are aberrantly expressed in various cancer types and have critical roles in their genesis and progression. miR-144 has been identified to be involved in the development of hepatocellular carcinoma and rectal cancer.

Purpose – The purpose of this paper is to test the effects of cigarette warning labels that used text-only or text-plus relevant graphics. The labels were framed in terms of either the negative consequences of smoking (loss frame) or the benefits of not smoking (gain frame). The role of smoking identity – the centrality of being a smoker to one's self-concept – in the effects of the warning labels was also examined. Design/methodology/approach – An experiment was conducted online with 132 college smokers. Participants were randomly assigned to viewing either graphic or text-only labels that were either gain or loss framed. Smoking identity was measure prior to viewing. Message evaluations and smoking intentions were assessed after exposure as dependent measures. Findings – A consistent interaction between graphics and framing emerged across a number of dependent measures. For graphic warning labels, the loss frame was more advantageous than the gain frame. For text-only warning labels, framing did not make any difference. This two-way interaction was further qualified by smoking identity for some, but not all, dependent measures. Practical implications – Findings from this study support the use of graphic warning labels that focus on the negative health consequences of smoking. Originality/value – Experimental research on graphic cigarette warning labels is limited and rarely considers the roles of framing and smoking identity. This study offered an initial test of the complex interaction among these message and audience variables as they jointly influence message reception and smoking intentions.

Green infrastructure (GI) design is advocated as a new paradigm for stormwater management, whereas current knowledge of GI design is mostly based on isolated design strategies used at small-scale sites. This study presents empirical findings from two watershed-scale community projects (89.4 km 2 and 55.7 km 2 ) in suburban Houston, Texas. The GI development integrates a suite of on-site, infiltration-based stormwater management designs, and an adjacent community development follows conventional drainage design. Parcel data were used to estimate the site impervious cover area. Observed streamflow and water quality data (i.e., NO 3 -N, NH 3 -N, and TP) were correlated with the site imperviousness. Results show that, as of 2009, the impervious cover percentage in the GI site (32.3%) is more than twice that of the conventional site (13.7%). However, the GI site's precipitation-streamflow ratio maintains a steady, low range, whereas this ratio fluctuates substantially in the conventional site, suggesting a "flashy" stream condition. Furthermore, in the conventional site, annual nutrient loadings are significantly correlated with its impervious cover percentage (p < 0.01), whereas in the GI site there is little correlation. The study concludes that integrated GI design can be effective in stormwater runoff reduction and water quality enhancement at watershed-scale community development.