The purpose of the present study was to compare the caries-preventive effect of a daily fluoride-containing lozenge and fortnightly rinses with a fluoride solution. A total of 670 children in first grade (7 years) and fourth grade (11 years) attending schools where the fluoride content of the drinking water was less than 0.25 ppm, were examined for dental caries. The subjects were stratified according to initial DMFS and randomly assigned to two groups. One group performed fortnightly rinses with 0.2% neutral sodium fluoride and the other group received a lozenge containing 1.1 mg sodium fluoride. Both procedures were only performed on schooldays and each group was given the corresponding placebo treatment. After 3 years, 499 children were available for reexamination. The average number of fluoride tablets consumed was 450 and of rinses performed was 40 per child for the entire study period. Statistical analysis showed a significantly lower increment of dental caries in children rinsing with 0.2% neutral sodium fluoride every 2nd week compared to children using a lozenge containing 1.1 mg sodium fluoride each school-day. The difference was most marked in the youngest age group. No statistically significant differences were found in teeth erupting during the study.
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