Cariostatic Effect of Daily Use of a Fluoride-Containing Lozenge Compared to Fortnightly Rinses with 0.2% Sodium Fluoride

Gadegaard, E; Mortensen, Birte

doi:10.1159/000260519

Cited by 17 publications

(7 citation statements)

References 5 publications

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“…The drop-out rate during the trial was a little lower than the 25-26% in some of our previous trials [Poulsen et al, 1981;Kirkegaard et al, 1986] and slightly higher for the 1989-92 cohort (23%) than for the 1990-93 cohort (17%). This difference may have been generated by the negative effect of the media's comments on the trial.…”

Section: Discussioncontrasting

confidence: 51%

Comparative Three-Year Caries Protection from an Aluminium-Containing and a Fluoride-Containing Toothpaste

Heidmann¹,

Poulsen²

1997

Caries Res

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In the present study, 2,087 fifth-graders (mean age: 12 years) from two cohorts entered a 3-year clinical toothpaste trial. The study subjects were randomly allocated to two groups: one group was a positive control using a 0.83% NaFPO₃ toothpaste, while the other group brushed with a test toothpaste containing 1.77% KA1(SO₄)₂. Both toothpastes were used unsupervised at home. One set of bite-wing radiographs was obtained at the beginning of the trial and another at the 3-year follow-up. Clinical registrations of caries were performed by the municipal dentists responsible for the child’s dental care. After 3 years, the mean caries increment was significantly higher in the group using the aluminium-containing toothpaste measured both clinically and radiographically.

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Section: Discussioncontrasting

confidence: 51%

Comparative Three-Year Caries Protection from an Aluminium-Containing and a Fluoride-Containing Toothpaste

Heidmann¹,

Poulsen²

1997

Caries Res

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“…The results of the Driscoll et al study contrast with those of the study of Poulsen et al (90), which was very similar in design, but used supplements with less fluoride, had a shorter duration, and studied older children.…”

Section: The Canes Reductions Listed Inmentioning

confidence: 75%

“…Poulsen et al (90) compared the effects of daily (school days only) 0.5 mg fluoride lozenges and biweekly 0.2 percent NaF mouthrinses administered at school. The study was well conducted: the participants were initially seven-and 11-year-olds; 499 were still available after three years.…”

Section: The Canes Reductions Listed Inmentioning

confidence: 99%

Fluoride Supplements in Caries Prevention: A Literature Review and Proposal for a New Dosage Schedule

Riordan

1993

J Public Health Dent

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Fluoride supplements have contributed significantly to caries prevention; however, better information about the dynamic nature of fluoride's effect on caries has made a reappraisal desirable. It seems, from a review of the literature, that the benefit from supplement use that can be expected today in populations in low-fluoride areas is small. Possible reasons include the low caries incidence in children of recent years. Few people are willing to use supplements with sufficient regularity to achieve an effect. The principal mode of action of fluoride in supplements, topical exposure of teeth to fluoride, can be achieved with toothpastes and other means. Supplement use has been associated with dental fluorosis in children. This is displeasing to look at and may put at risk the undoubted benefits of water fluoridation if the public associates fluoride with negative cosmetic effects. This reason alone should be sufficient to compel a reconsideration of existing recommendations. An appropriate new dosage schedule for fluoride supplements should be aimed only at identifiable high caries-risk individuals, not at groups defined by age or residence and should result in much lower fluoride intake in the age span birth-eight years than many current recommendations. It should start at six months or later, expressly recommend lozenges rather than tablets for swallowing to maximize the topical effect, stipulate that the maximum fluoride ion content of a tablet be 0.50 mg to reduce the chances of fluorosis and overconsumption, and have no upper age limit, as caries risk may occur at any age. A dosage schedule meeting these requirements is proposed.

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“…The findings of the other study, conducted by Poulsen et al, also are in disagreement with those of the Springfield study (15). In that study, the caries-preventive effects of chewing and swallowing a lozenge containing0.5 mg F each day in school were compared with those of fortnightly use in school of a mouthrinse containing 0.2 percent NaF.…”

Section: "The Ability To Discern Clear-cut Distinctions Among the Thrmentioning

confidence: 79%

A Comparison of the Caries‐preventive Effects of Fluoride Mouthrinsing, Fluoride Tablets, and Both Procedures Combined: Final Results after Eight Years

Driscoll

Nowjack‐Raymer²,

Selwitz³

et al. 1992

J Public Health Dent

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This paper presents final results of an eight-year clinical trial designed to compare the caries-preventive benefits of two self-administered fluoride procedures when used separately and in combination with one another. Children in kindergarten and first grade residing in Springfield, Ohio, a nonfluoridated community, were assigned randomly within school to one of three groups that either (a) rinsed once a week in school with a 0.2 percent neutral NaF solution; (b) chewed, rinsed with, and then swallowed daily in school a neutral 2.2 mg NaF tablet; or (c) carried out both procedures. At baseline (1981), 1,640 participants were examined clinically using the DMF surface index. Findings for 640 children remaining after eight years show that subjects in the combination group experienced a mean caries increment of 2.40 DMFS, 15.2 percent lower than the mean score of 2.83 DMFS for children in the tablet group and 32.8 percent lower than the 3.57 DMFS for those in the rinse group. Only the difference in incremental caries scores between the combined fluoride procedure and the fluoride rinse was statistically significant (P less than .05). The pattern of these findings is similar to that found on the two interim examinations. Even though the combined regimen showed an additional caries-preventive benefit compared with the rinse, considerations of cost effectiveness and feasibility do not support changing an ongoing rinse program to one that employs both procedures. For new programs the best choice appears to be the tablet procedure alone.

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Cariostatic Effect of Daily Use of a Fluoride-Containing Lozenge Compared to Fortnightly Rinses with 0.2% Sodium Fluoride

Cited by 17 publications

References 5 publications

Comparative Three-Year Caries Protection from an Aluminium-Containing and a Fluoride-Containing Toothpaste

Comparative Three-Year Caries Protection from an Aluminium-Containing and a Fluoride-Containing Toothpaste

Fluoride Supplements in Caries Prevention: A Literature Review and Proposal for a New Dosage Schedule

A Comparison of the Caries‐preventive Effects of Fluoride Mouthrinsing, Fluoride Tablets, and Both Procedures Combined: Final Results after Eight Years

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