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Mycobacterium tuberculosis infection is a common infection in developing countries, including India. It can induce several cutaneous reactions such as erythema nodosum, and erythema induratum; however, association of tuberculosis with Sweet's syndrome (also known as acute febrile neutrophilic dermatosis) is extremely rare. Here we present an interesting case of sputum-positive pulmonary tuberculosis with Sweet's syndrome. A 55-year-old female who was receiving a regimen of four antitubercular drugs (isoniazid, rifampicin, pyrazinamide, ethambutol-HRZE) for six weeks for sputum-positive pulmonary tuberculosis developed new onset high-grade fever for 15 days along with multiple reddish brown plaques and nodules involving the face as well as all four limbs of the body. Histopathology of the skin lesion was suggestive of Sweet's syndrome. The patient responded well to immunosuppressive steroid therapy.

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Introduction: The Mediastinum is the central part of thorax where various organs are located which gives rise to various neoplastic and non-neoplastic lesions.Accurate diagnosis is important to formulate proper therapeutic strategy and predict prognosis. Studies are very few in this part of the country. Objective: To analyse presentation of patients with Meditastinal Mass and to classify according to the location of mass. Also, to document Malignant versus Non-malignant nature oflesions. Methods: Total 33 patients with mediastinal masses diagnosed by Imagingand Histopathological study were taken up consecutively in the study during one year of study. Results: of the 33 cases, 21 were male (63.6%) and 12 were female (36.4%), Male; female ratio being 1.8: 1. Age ranged from 14 years to 72 years maximum of 8 Patients (24.2%) in the 12-20 years of age group. 57% of the masses were malignant and 43% were benign. Most common lesion was Lymphoma in 10 cases (30.3%) followed by8 cases of Thymic tumours (24.2%). Metastatic Carcinoma was found in 6 patients (18.2%) followed by 3 patients of Germ cell tumours.One case each of Neurofibroma, Neurolipoma and 6 are of different less common category. Compartment wise, 9 cases (27.3%) were in Anterior Compartment, 1 (3%) case in Post Compartment, 3 case in superior mediastinum, 6 case in Middle mediastinum. Maximum cases, 14(42.5%) were occupying Multiple Compartments. Most common symptom was cough (72%). Pleural and Pericardial effusions were common complication of malignant lesions contributing 7 out of 19(36%) and 3 out of 19(17%) respectively. Conclusion: Mediastinal masses creates a diagnostic dilemma to the clinician. Uncommon cause of common symptoms like cough and common presentation of pleural or pericardial effusion may have Mediastinal mass behind the screen.

Introduction: The prevalence of LV dysfunction is probably high in COPD patients because this condition shares common risk factors. The diagnosis of left heart failure is difficultin the early phases of COPD and also during exacerbation due to similarities in signs and symptoms. Bio-markers like hsCRP is found to be elevated in stable phase as well as in exacerbation of COPD. Objectives: To assess LV Dysfunction (Systolic and Diastolic) and to correlate Age, Symptoms, Duration and stage of illness, CRP with LV Dysfunction. Methods: Total 100 patients of which 50 were age and sex matched controls not having COPD complying with Inclusion and Exclusion Criteria. After taking history and clinical examination they were evaluated for COPD and Left ventricular Dysfunction using PFT and Echocardiogram. Results: Out of 50 patients, 37 patients (74%) had Diastolic dysfunction, of them 2 patients had Systolic dysfunction also. 13 patients were normal. In the control group only 4 had Diastolic Dysfuncion.CRP was high in 35% (70%) of patients. In the higher age group of 50-60 years Diastolic dysfunction was significant. In patients of GOLD stage IV 5 out of 5 patients (100%) whereas in GOLD stage I and II it was in 1 case (16.66%) and21 case (80.76%) respectively. While comparing with the control group incidence of LV dysfunction parameters and CRP is more in case group. Conclusion: There is increased incidence ofLV Diastolic dysfunction and also with advanced GOLD stage. CRP also correlates well LVDD. Therefore it is pertinent to explore LVDD in all patients with acute exacerbation of COPD and advanced disease stage.